160707-37-9Relevant articles and documents
An Improved and Efficient Process for the Production of Highly Pure Dexmethylphenidate Hydrochloride
Xing, Long-Xuan,Shen, Cheng-Wu,Sun, Yuan-Yuan,Huang, Lei,Zheng, Yong-Yong,Li, Jian-Qi
, p. 1298 - 1303 (2017)
The present work describes an efficient and commercially viable process for the synthesis of dexmethylphenidate hydrochloride (1), a mild nervous system stimulant. The overall yield is 23% with ~99.9% purity (including seven chemical steps). Formation and control of possible impurities are also described in this report.
METHOD FOR THE PRODUCTION OF D-THREO-2-PHENYL-2-PIPERIDINE-2-YL ACETATES
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Page/Page column 9, (2008/06/13)
Disclosed is a method for producing d-threo-[R(R*,R*)]-2-phenyl-2-piperidine-2-yl acetate and the acid addition salts thereof by converting d-threo-[R(R*,R*)]-2-phenyl-2-piperidine-2-yl ethanoic acid or an acid addition salt thereof into the corresponding
Processes and intermediates for resolving piperidyl acetamide stereoisomers
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, (2008/06/13)
Processes and intermediates for preparing 2-substituted piperidines such as 2-substituted d-threo piperidines are provided, including processes and intermediates for resolution of piperidyl acetamide stereoisomers.