160911-42-2 Usage
Uses
Used in Pharmaceutical Industry:
Imidazo[1,2-b]pyridazine-2-carboxylic acid (9CI) is used as a pharmaceutical agent for its potential to inhibit certain biological processes. It is being studied for its therapeutic effects on a range of conditions, including cancer and autoimmune diseases, due to its unique molecular structure and biological activity.
Used in Drug Development:
In the field of drug development, Imidazo[1,2-b]pyridazine-2-carboxylic acid (9CI) serves as a key compound for the creation of new medications. Its heterocyclic nature allows for the design of drugs that can target specific pathways or receptors, offering potential treatments for various diseases where existing therapies may be insufficient or have adverse side effects.
Used in Medicinal Chemistry Research:
Imidazo[1,2-b]pyridazine-2-carboxylic acid (9CI) is utilized as a subject of research in medicinal chemistry to explore its potential interactions with biological targets. This research is crucial for understanding the compound's mechanism of action and for optimizing its properties to enhance its therapeutic efficacy and safety profile.
Check Digit Verification of cas no
The CAS Registry Mumber 160911-42-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,0,9,1 and 1 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 160911-42:
(8*1)+(7*6)+(6*0)+(5*9)+(4*1)+(3*1)+(2*4)+(1*2)=112
112 % 10 = 2
So 160911-42-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H5N3O2/c11-7(12)5-4-10-6(9-5)2-1-3-8-10/h1-4H,(H,11,12)
160911-42-2Relevant articles and documents
Research on heterocyclic compounds. XXXVIII. Synthesis and pharmacological activity of imidazo[1,2-b]pyridazine-2-carboxylic derivatives
Luraschi,Arena,Sacchi,Laneri,Abignente,Avallone,D'Amico,Berrino,Rossi
, p. 213 - 217 (2007/10/03)
A series of imidazo[1,2-b]pyridazine-2-carboxylic acids, esters and amides was synthesized and tested for antiinflammatory, analgesic and ulcerogenic activities. The ethyl esters were prepared by cyclocondensation of some 3-aminopyridazines with ethyl bromopyruvate, followed by hydrolysis or ammonolysis in order to obtain the corresponding acids and amides. The inhibitory activity on the carrageenaninduced edema in the rat paw and on writhes induced by acetic acid in mice was evaluated, as well as the ulcerogenic action on the rat gastric mucosa. The pharmacological activity was discussed in terms of structure-activity relationships. In particular, the analgestic activity shown by these carboxylic derivatives was compared with that found in other series of imidazo[1,2-b]pyridazine analogues previously examined.
