1609552-01-3

Basic information

• Product Name: 2-(3-oxo-1,2-benzothiazol-2(3H)-yl)-N-(5-(m-tolyl)-1,3,4-thiadiazole-2-yl)acetamide
• Synonyms: 2-(3-oxo-1,2-benzothiazol-2(3H)-yl)-N-(5-(m-tolyl)-1,3,4-thiadiazole-2-yl)acetamide
• CAS NO: 1609552-01-3
• Molecular Weight: 382.467
• Mol File: 1609552-01-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(3-oxo-1,2-benzothiazol-2(3H)-yl)-N-(5-(m-tolyl)-1,3,4-thiadiazole-2-yl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-oxo-1,2-benzothiazol-2(3H)-yl)-N-(5-(m-tolyl)-1,3,4-thiadiazole-2-yl)acetamide(1609552-01-3)
• EPA Substance Registry System: 2-(3-oxo-1,2-benzothiazol-2(3H)-yl)-N-(5-(m-tolyl)-1,3,4-thiadiazole-2-yl)acetamide(1609552-01-3)

Safety Data

• Hazardous Substances Data: 1609552-01-3(Hazardous Substances Data)

Upstream product

• 99-04-7 m-Toluic acid 
• 2634-33-5 1,2-benzisothiazolin-3-one 
• 76074-47-0 5-(3-methylphenyl)-1,3,4-thiadiazol-2-amine 
• 82152-06-5 2-(3-Oxo-3h-benzo[d]isothiazol-2-yl)-acetic acid 

Relevant articles and documents

1, 3, 4- [...] and isothiazolinone acetyl amine derivatives and its synthetic method

The invention relates to a 1,3,4-thiadiazole benzisothiazolinone acetamide derivative and a synthesis method thereof. The 1,3,4-thiadiazole benzisothiazolinone acetamide derivative has a structural formula shown in a drawing, wherein R is hydrogen, 3-methyl, 4-methoxy, 4-chloro or 2-bromo-4-nitro. The synthesis method comprises the steps of dissolving substituted 2-amino-5-substituted phenyl-1,3,4-thiadiazole and benzisothiazolin-3-one-2-yl acetic acid with an organic solvent, adding a condensing agent, reacting for 16-24 hours at the temperature of 10-30 DEG C, pouring a solution into water after the reaction is completed, and precipitating solids; filtrating, washing, drying, and then carrying out column chromatography, thereby obtaining the 1,3,4-thiadiazole benzisothiazolinone acetamide derivative which has good biological activity. According to the 1,3,4-thiadiazole benzisothiazolinone acetamide derivative and the synthesis method thereof, the reaction conditions are mild, the reacting operation is simple and convenient, and the reaction yield is relatively high.