1612222-92-0

Basic information

• Product Name: C₁₃H₁₂N₂O₂
• Synonyms: C₁₃H₁₂N₂O₂
• CAS NO: 1612222-92-0
• Molecular Weight: 228.25
• Mol File: 1612222-92-0.mol

Chemical Properties

• CAS DataBase Reference: C₁₃H₁₂N₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₁₂N₂O₂(1612222-92-0)
• EPA Substance Registry System: C₁₃H₁₂N₂O₂(1612222-92-0)

Safety Data

• Hazardous Substances Data: 1612222-92-0(Hazardous Substances Data)

Upstream product

• 694-59-7 pyridine N-oxide 
• 77086-38-5 ketene t-butyldimethylsilyl methyl acetal 

Relevant articles and documents

Expedient synthesis of α-(2-azaheteroaryl) acetates via the addition of silyl ketene acetals to azine- N -oxides

A new and expedient synthesis of α-(2-azaheteroaryl) acetates is presented. The reaction proceeds rapidly under mild conditions via the addition of silyl ketene acetals to azine-N-oxides in the presence of the phosphonium salt PyBroP. This procedure affords diverse α-(2-azaheteroaryl) acetates which are highly desirable components/building blocks in molecules of pharmaceutical interest but are traditionally challenging to synthesize via contemporary methods. The reaction optimization and mechanism as well as a novel electronically enhanced PyBroP derivative are described.