16139-79-0

Basic information

• Product Name: DIPHENYLPHOSPHONOACETIC ACID ETHYL ESTER
• Synonyms: ETHYL DIPHENYLPHOSPHONOACETATE;DIPHENYLPHOSPHONOACETIC ACID ETHYL ESTER;Diphenylphsphonoacetic acid ethyl ester;Horner-emmonsreagent;Ethyl Diphenylphosphonoacetate [Horner-Emmons Reagent];Ethyl 2-(diphenoxyphosphoryl)
• CAS NO: 16139-79-0
• Molecular Formula: C₁₆H₁₇O₅P
• Molecular Weight: 320.28
• Product Categories: Horner-Emmons Reaction;Synthetic Organic Chemistry;Wittig & Horner-Emmons Reaction
• Mol File: 16139-79-0.mol
• Article Data: 13

Chemical Properties

• Melting Point: 81-82 °C
• Boiling Point: 220 °C / 3mmHg
• Flash Point: 223.397°C
• Appearance: /
• Density: 1.22
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.5320-1.5360
• Storage Temp.: 0-10°C
• CAS DataBase Reference: DIPHENYLPHOSPHONOACETIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: DIPHENYLPHOSPHONOACETIC ACID ETHYL ESTER(16139-79-0)
• EPA Substance Registry System: DIPHENYLPHOSPHONOACETIC ACID ETHYL ESTER(16139-79-0)

Safety Data

• Hazardous Substances Data: 16139-79-0(Hazardous Substances Data)

Usage

General Description

Diphenylphosphonoacetic acid ethyl ester is a chemical compound that is commonly used as a stabilizer in the production of plastics, polymers, and other industrial materials. It belongs to the group of organophosphates, which are commonly used as flame retardants and plasticizers. The compound is also commonly used as a catalyst and intermediate in the synthesis of various chemical products. It is important to handle this chemical with caution as it can be toxic and harmful if not handled properly. Additionally, it is important to follow safety guidelines and regulations when using this compound in industrial applications.

InChI:InChI=1/C16H17O5P/c1-2-19-16(17)13-22(18,20-14-9-5-3-6-10-14)21-15-11-7-4-8-12-15/h3-12H,2,13H2,1H3

Upstream product

• 4712-55-4 diphenyl hydrogen phosphite 
• 105-36-2 ethyl bromoacetate 
• 2161-16-2 phosphorous acid ethyl ester-diphenyl ester 
• 623-73-4 diazoacetic acid ethyl ester 
• 539-74-2 Ethyl 3-bromopropionate 
• 36957-54-7 ethyl 2-(dichlorophosphinyl)acetate 
• 139-02-6 sodium phenoxide 
• 838-85-7 diphenyl hydrogen phosphate 
• 108-95-2 phenol 
• 791130-78-4 ethyl dibromo(diphenylphosphono)acetate 
• 7526-26-3 diphenyl methylphosphonate 
• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 7367-88-6 ethyl (E)-2-decenate 
• 7367-88-6 (Z)-dec-2-enoic acid ethyl ester 
• 216519-94-7 ethyl 2-(diphenylphosphono)-2-isopropylacetate 
• 216519-84-5 ethyl 2-(diphenoxyphosphoryl) propanoate 
• 247200-36-8 Ethyl (4S,2Z)-6-methyl-4-[(4-methylphenylsulfonyl)amino]hept-2-enoate 
• 247200-54-0 Ethyl (4S,2E)-6-methyl-4-[(4-methylphenylsulfonyl)amino]hept-2-enoate 
• 247200-33-5 Ethyl (4S,2Z)-5-methyl-4-[(2,4,6-trimethylphenylsulfonyl)amino]hex-2-enoate 
• 247200-34-6 Ethyl (4S,2Z)-4-[(4-methoxy-2,3,6-trimethylphenylsulfonyl)amino]-5-methylhex-2-enoate 
• 247200-35-7 Ethyl (4S,5S,2Z)-5-methyl-4-[(4-methoxy-2,3,6-trimethylphenylsulfonyl)amino]hept-2-enoate 
• 88842-13-1 (Z-)-ethyl 5-phenylpent-2-enoate 
• 55282-95-6 ethyl (2E)-5-phenylpent-2-enoate 
• 33491-30-4 8-bromo-2H-1-benzopyran-2-one 
• 2725-81-7 6-nitrocoumarin 
• 197314-77-5 5-nitro-2-hydroxy-(E)-cinnamic acid methyl ester 

Relevant articles and documents

Combining two-directional synthesis and tandem reactions: A short formal synthesis of halichlorine

A short and efficient synthesis of an advanced intermediate (1) in the Clive route to halichlorine has been achieved in 12 steps and 13.2% yield by a combined two-directional synthesis/tandem reaction strategy.

Detection of a New Piperideine Alkaloid in the Pygidial Glands of Some Stenus Beetles

Rove beetles of the genus Stenus produce and store bioactive alkaloids like stenusine (3), 3-(2-methylbut-1-enyl)pyridine (4), and cicindeloine (5) in their pygidial glands to protect themselves from predation and microorganismic infestation. The biosynth

Intramolecular Pd-Catalyzed Arylation of 1-Amidosugars: A New Route to N-Glycosyl Quinolin-2-ones

The synthesis of N-glycosylated quinolin-2-ones via an intramolecular N-arylation of glycosylamides is reported. The coupling involves the use of only Pd(OAc)2 as the catalyst and nBu4NOAc as the base in 1,4-dioxane. This versatile approach allows the synthesis of various N-glycosylated quinolin-2-ones with exclusive α or β selectivity.

Cis-specific hydrofluorination of alkenylarenes under palladium catalysis through an ionic pathway

This paper describes the hydrofluorination of alkenes through sequential H- and F+ addition under palladium catalysis. The reaction is cis specific, thus providing access to benzylic fluorides. The mechanism of this reaction involves an ionic pathway and is distinct from known hydrofluorinations involving radical intermediates. The first catalytic enantioselective hydrofluorination is also disclosed. See attached PdF: A series of benzylic fluorides was prepared by hydrofluorination which proceeds through a PdII/IV catalytic manifold. The method is mechanistically distinct from previously reported radical hydrofluorination, and is characterized by its clean regioselectivity and unique cis stereospecificity. The first example of enantioselective net HF addition onto 2-vinylnaphthalene is also disclosed.