1619982-79-4

Basic information

• Product Name: [(1S,4aS,8aS)-2,5,5,8a-tetramethyl-1,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl](3-methoxy-5-methylphenyl)methanone
• Synonyms: [(1S,4aS,8aS)-2,5,5,8a-tetramethyl-1,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl](3-methoxy-5-methylphenyl)methanone
• CAS NO: 1619982-79-4
• Molecular Weight: 340.506
• Mol File: 1619982-79-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [(1S,4aS,8aS)-2,5,5,8a-tetramethyl-1,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl](3-methoxy-5-methylphenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: [(1S,4aS,8aS)-2,5,5,8a-tetramethyl-1,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl](3-methoxy-5-methylphenyl)methanone(1619982-79-4)
• EPA Substance Registry System: [(1S,4aS,8aS)-2,5,5,8a-tetramethyl-1,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl](3-methoxy-5-methylphenyl)methanone(1619982-79-4)

Safety Data

• Hazardous Substances Data: 1619982-79-4(Hazardous Substances Data)

Upstream product

• 1619982-78-3 (1R,2R,4aS,8aS)-1-[(3-methoxy-5-methylphenyl)carbonyl]-2,5,5,8a-tetramethyldecahydronaphthalen-2-ol 
• 1000009-66-4 (1S,2R,4aS,8aS)-1-[hydroxy(3-methoxy-5-methylphenyl)methyl]-2,5,5,8a-tetramethyldecahydronaphthalen-2-ol 

Downstream Products

• 1619982-81-8 3-{[(4aS,8aS)-2,5,5,8a-tetramethyl-3,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]carbonyl}-5-methylphenol 
• 1619982-80-7 3-{[(4aS,8aS)-2,5,5,8a-tetramethyl-1,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]carbonyl}-5-methylphenol 
• 1619983-19-5 (4S,4aS,8aS)-4-[(3-methoxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalene-2-carbonitrile 
• 1619983-20-8 (3S,4S,4aS,8aS)-4-[(3-methoxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalene-2-carboxamide 
• 1619983-22-0 (3S,4S,4aS,8aS)-4-[(3-hydroxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalene-2-carboxamide 
• 1619984-10-9 [(1S,4aS,8aS)-3-(methoxymethylidene)-2,5,5,8a-tetramethyl-decahydronaphthalen-1-yl](3-methoxy-5-methylphenyl)methanone 
• 1619983-24-2 (3S,4S,4aS,8aS)-4-[(3-methoxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalene-2-carboxylicacid 
• 1619983-26-4 (3S,4S,4aS,8aS)-4-[(3-hydroxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalene-2-carboxylic acid 
• 1619982-82-9 (2R,3R,4S,4aS,8aS)-4-[(3-methoxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalen-2-ol 
• 1619982-83-0 (3R,4S,4aS,8aS)-4-[(3-methoxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalen-2-one 
• 1619982-84-1 (3S,4S,4aS,8aS)-4-[(3-hydroxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalen-2-one 
• 1619984-05-2 tertbutyl N-(3-{[(3S,4S,4aS,8aS)-4-[(3-methoxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyl-decahydronaphthalen-2-yl]amino}propyl)carbamate 
• 1619984-07-4 tert-butyl N-[(4S,4aS,8aS)-4-[(3-hydroxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalen-2-yl]carbamate 
• 1619982-95-4 (3S,4S,4aS,8aS)-4-[(3-hydroxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalen-2-ol 

Relevant articles and documents

SHIP1 MODULATORS AND METHODS RELATED THERETO

Compounds of formula (I): [Formula should be inserted here]; where [Formula should be inserted here], n, R1, R4a, R4b, R5, R7 and R8 are defined herein, or pharmaceutically acceptable salts thereof, are described herein. The disclosed compounds have activity as SHIP1 modulators, and thus may be used to treat any of a variety of diseases, disorders or conditions that would benefit from SHIP1 modulation. Compositions comprising a compound of formula (I) in combination with a pharmaceutically acceptable carrier or diluent are also disclosed, as are methods of SHIP1 modulation by administration of such compounds to an animal in need thereof.