1620-14-0

Basic information

• Product Name: DIETHYLAMINOACETONE
• Synonyms: DIETHYLAMINOACETONE;1-(Diethylamino)acetone;2-Propanone, 1-(diethylamino)-;1-Diethylamino-2-propanone;Diethylaminoacetone,98%;DiethylaMinoacetone, 98% 5ML;(Diethylamino)acetone 96%;1-(diethylamino)propan-2-one
• CAS NO: 1620-14-0
• Molecular Formula: C₇H₁₅NO
• Molecular Weight: 129.2
• EINECS: 216-583-1
• Product Categories: C7 to C8;Carbonyl Compounds;Ketones
• Mol File: 1620-14-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 64 °C16 mm Hg(lit.)
• Flash Point: 101 °F
• Appearance: /
• Density: 0.832 g/mL at 25 °C(lit.)
• Vapor Pressure: 1.64mmHg at 25°C
• Refractive Index: n20/D 1.425(lit.)
• Storage Temp.: 0-6°C
• PKA: 8.47±0.25(Predicted)
• CAS DataBase Reference: DIETHYLAMINOACETONE(CAS DataBase Reference)
• NIST Chemistry Reference: DIETHYLAMINOACETONE(1620-14-0)
• EPA Substance Registry System: DIETHYLAMINOACETONE(1620-14-0)

Safety Data

• Hazard Codes: Xi,C
• Statements: 10-36/37/38
• Safety Statements: 16-26-36/37/39
• RIDADR: UN 1224 3/PG 3
• WGK Germany: 3
• HazardClass: 3.2
• PackingGroup: III
• Hazardous Substances Data: 1620-14-0(Hazardous Substances Data)

Usage

Chemical Properties

clear yellow to brown liquid

InChI:InChI=1/C7H15NO/c1-4-8(5-2)6-7(3)9/h4-6H2,1-3H3/p+1

Upstream product

• 107-19-7 propargyl alcohol 
• 109-89-7 diethylamine 
• 2684-62-0 diazoacetone 
• 56-81-5 glycerol 
• 5573-55-7 N,N-diethyl-1,1-dimethyl-1-(prop-1-en-2-yloxy)silanamine 
• 13138-17-5 1-Diaethylamino-2,5-dimethyl-2-hydroxy-hexin-⁽³⁾ 
• 598-31-2 1-bromoacetone 
• 78-95-5 chloroacetone 
• 4079-68-9 N,N-diethyl-2-propynylamine 

Downstream Products

• 109-89-7 diethylamine 
• 78-98-8 2-oxopropanal 
• 62664-60-2 ethyl 2-benzoyl-4-oxopentanoate 
• 351031-95-3 ethyl 2-benzoyl-3-methyl-5-oxo-pentanoate 
• 5893-24-3 acetic acid-[N'-(β-diethylamino-isopropyl)-hydrazide] 
• 95368-87-9 1-Methyl-3-dimethylamino-methyl-2-<β-diethylamino-α-hydroxy-isopropyl>indol 
• 761-21-7 1-diethylamino-2-chloropropane 
• 115000-71-0 diethyl-(2-methyl-hexyl)-amine 
• 101455-05-4 (E)-1-Diethylamino-4-(4-methoxy-phenyl)-but-3-en-2-ol 
• 108490-26-2 1-Diethylamino-2-(methyl-phenyl-p-tolyl-silanyl)-propan-2-ol 
• 108490-27-3 2-(Cyclohexyl-methyl-phenyl-silanyl)-1-diethylamino-propan-2-ol 
• 108490-25-1 1-Diethylamino-2-(methyl-diphenyl-silanyl)-propan-2-ol 
• 71151-31-0 1-Diaethylamino-2-benzyl-propanol-⁽²⁾ 
• 66031-40-1 1-Diaethylamino-2-cyclohexyl-propanol-⁽²⁾ 

Relevant articles and documents

ON THE SPECIFICITY OF THE TTC REACTION. 2. THE TTC REACTION OF

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Flexible stereoselective functionalizations of ketones through umpolung with hypervalent iodine reagents

The functionalization of carbonyl compounds in the α-position has gathered much attention as a synthetic route because of the wide biological importance of such products. Through polarity reversal, or "umpolung", we show here that typical nucleophiles, such as oxygen, nitrogen, and even carbon nucleophiles, can be used for addition reactions after tethering them to enol ethers. Our findings allow novel retrosynthetic planning and rapid assembly of structures previously accessible only by multistep sequences. A Nu approach: An efficient α-functionalization of ketones with a range of simple and useful nucleophiles is possible by using hypervalent iodine reagents (see scheme; Nu′ can be the Nu itself or a protected form of this nucleophile group).

Highly chemoselective α-diazo carbonyl insertion reactions into N-H and S-H bonds catalysed by [RuCl(η5-C5H5)(PPh3)2]

Complex [RuCl(η5-C5H5)(PPh3)2], in chloroform at 60 deg C, catalyses the chemoselective insertion of α-diazo carbonyl compounds into N-H and S-H bonds to afford α-keto-amines and α-keto-thioethers.