1622-67-9

Basic information

• Product Name: 1,5-dihydro-3-isopropyl-8-methyl-[1,3]dioxepino[5,6-c]pyridin-9-ol
• Synonyms: 1,5-dihydro-3-isopropyl-8-methyl-[1,3]dioxepino[5,6-c]pyridin-9-ol;1,5-Dihydro-8-methyl-3-(1-methylethyl)-[1,3]dioxepino[5,6-c]pyridin-9-ol;Einecs 216-598-3
• CAS NO: 1622-67-9
• Molecular Formula: C₁₂H₁₇NO₃
• Molecular Weight: 223.26828
• EINECS: 216-598-3
• Mol File: 1622-67-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 396.6°Cat760mmHg
• Flash Point: 193.6°C
• Appearance: /
• Density: 1.138g/cm³
• Vapor Pressure: 7.39E-07mmHg at 25°C
• Refractive Index: 1.527
• CAS DataBase Reference: 1,5-dihydro-3-isopropyl-8-methyl-[1,3]dioxepino[5,6-c]pyridin-9-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-dihydro-3-isopropyl-8-methyl-[1,3]dioxepino[5,6-c]pyridin-9-ol(1622-67-9)
• EPA Substance Registry System: 1,5-dihydro-3-isopropyl-8-methyl-[1,3]dioxepino[5,6-c]pyridin-9-ol(1622-67-9)

Safety Data

• Hazardous Substances Data: 1622-67-9(Hazardous Substances Data)

Usage

General Description

"1,5-dihydro-3-isopropyl-8-methyl-[1,3]dioxepino[5,6-c]pyridin-9-ol" is a chemical compound with a complex molecular structure. It consists of a 1,3-dioxepane ring fused to a pyridine ring, with a hydroxyl group attached at the 9th position. The presence of an isopropyl and a methyl group in the molecule adds to its complexity. This chemical may have potential applications in pharmaceutical or industrial settings, but further research would be needed to determine its specific properties and uses.

InChI:InChI=1/C12H17NO3/c1-7(2)12-15-5-9-4-13-8(3)11(14)10(9)6-16-12/h4,7,12,14H,5-6H2,1-3H3

Upstream product

• 19104-68-8 4-methyl-5-propoxyoxazole 
• 5417-35-6 2-isopropyl-4,7-dihydro-[1,3]dioxepine 
• 7625-53-8 rac-Ala-OMe 
• 717916-87-5 3-isopropyl-1,5-dihydro[1,3]dioxepino-3-methyl-4-n-butoxy-7-oxa-2-azabicyclo[2.2.1]hept-2-ene 
• 5006-20-2 5-ethoxy-4-methyl-oxazole 
• 5205-63-0 Diels-Alder adduct 

Downstream Products

• 92671-67-5 8-methyl-3-(propan-2-yl)-1H,3H,5H-[1,3]dioxepino[5,6-c]pyridin-9-yl acetate 
• 65-23-6 5-hydroxy-6-methyl-3,4-pyridinedimethanol 
• 58-56-0 pyridoxal hydrochloride 
• 69022-73-7 3-isopropyl-8-methyl-9-prop-2-ynyloxy-1,5-dihydro-[1,3]dioxepino[5,6-c]pyridine 

Relevant articles and documents

New synthetic route of vitamine B6

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MANUFACTURE OF VITAMIN B6

A process for manufacturing a 3-unsubstituted, 3-monosubstituted or 3,3-disubstituted 9-acyloxy-1,5-dihydro-8--methylpyrido[3,4-e] [1,3]dioxepin (I) and optionally for manufacturing pyridoxine involves performing an addition reaction between a 4-methyl-5-alkoxy-oxazole (II) and a 2-unsubstituted, 2-monosubstituted or 2,2-disubstituted 4,7-dihydro-(1,3)-dioxepin (III) in the substantial absence of a solvent and a catalyst to give a product mixture consisting essentially of the appropriate Diels-Alder adduct (IV) in a major proportion and the appropriate 3--unsubstituted, 3-monosubstituted or 3,3-disubstituted 1,5-dihydro-8-methylpyrido[3,4-e] [1,3]dioxepin 9-ol (V) in a minor proportion, removal of a substantial proportion of the unreacted oxazole and dioxapin starting materials from the product mixture by distillation under reduced pressure, addition of a substantially anhydrous organic acid to said product mixture and rearrangement of the Diels-Alder adduct IV to further V in the presence of said substantially anhydrous organic acid with removal of the generated alkanol by distillation under reduced pressure, and acylation of the resultingly enriched quantity of V with an added carboxylic acid anhydride to produce the desired I, and optionally converting this so-manufactured acylation product I to pyridoxine by acid hydrolysis for achieving deprotection and deacylatiom. Pyridoxine is a well known form of vitamin B6 with well established utility.