16222-10-9

Basic information

• Product Name: phenacyl phenyl sulfide
• Synonyms: Phenyl(2-oxo-2-phenylethyl) sulfide;α-(Phenylthio)acetophenone;Ethanone, 1-phenyl-2-(phenylthio)-;phenacyl phenyl sulfide;(Phenylthio)acetylbenzene;1-Phenyl-2-(phenylthio)ethanone
• CAS NO: 16222-10-9
• Molecular Formula: C₁₄H₁₂OS
• Molecular Weight: 228.31
• Mol File: 16222-10-9.mol
• Article Data: 101

Chemical Properties

• Boiling Point: 367.1°Cat760mmHg
• Flash Point: 195.7°C
• Appearance: /
• Density: 1.17g/cm³
• Vapor Pressure: 1.39E-05mmHg at 25°C
• Refractive Index: 1.626
• CAS DataBase Reference: phenacyl phenyl sulfide(CAS DataBase Reference)
• NIST Chemistry Reference: phenacyl phenyl sulfide(16222-10-9)
• EPA Substance Registry System: phenacyl phenyl sulfide(16222-10-9)

Safety Data

• Hazardous Substances Data: 16222-10-9(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 35, p. 2195, 1994 DOI: 10.1016/S0040-4039(00)76794-3

InChI:InChI=1/C14H12OS/c15-14(12-7-3-1-4-8-12)11-16-13-9-5-2-6-10-13/h1-10H,11H2

Upstream product

• 3282-32-4 2-diazo-acetophenone 
• 108-98-5 thiophenol 
• 532-27-4 1-chloroacetophenone 
• 930-69-8 sodium thiophenolate 
• 3111-52-2 potassium thiophenolate 
• 70-11-1 α-bromoacetophenone 
• 1191-99-7 2,3-dihydro-2H-furan 
• 64340-80-3 Dimethyl-(1-phenyl-vinyloxy)-silane 
• 931-59-9 benzenesulfenyl chloride 
• 93-58-3 benzoic acid methyl ester 
• 30536-77-7 <(phenylthio)(trimethylsilyl)methyl>lithium 
• 93-89-0 benzoic acid ethyl ester 
• 13307-75-0 (phenylthio)methyllithium 
• 22805-27-2 ω,ω-bis(phenylthio)acetophenone 

Downstream Products

• 1207-95-0 2-phenylbenzo[b]thiophene 
• 14315-12-9 3-phenyl-1-benzothiophene 
• 102555-70-4 3-phenyl-5-phenylsulfanyl-benzo[b]thiophene 
• 67210-34-8 1-phenyl-2-phenylsulfanyl-ethanol 
• 34161-32-5 4-phenyl-5-phenylsulfanyl-thiazol-2-ylamine 
• 40390-78-1 [(1-phenylethyl)thio]benzene 
• 35572-11-3 α-bromo-α-(phenylsulfanyl)acetophenone 
• 81239-24-9 1-<1-phenyl-2-(phenythio)ethenyl>pyrrolidine 
• 125442-82-2 3-(2-Oxo-2-phenyl-1-phenylsulfanyl-ethyl)-cyclopentanone 
• 84538-93-2 phenyl 3-phenylbut-3-enyl sulfide 
• 79772-18-2 4-oxo-4-phenyl-3-(phenylthio)butanoic acid 
• 129363-78-6 ethyl 2-(dimethylamino)-6-phenyl-6-oxo-5-(phenylthio)-2,4-hexadienoate 
• 3406-03-9 2-(phenylsulfonyl)acetophenone 
• 6099-23-6 1-(phenylsulfinyl)acetophenone 

Relevant articles and documents

Terpene ligands as the basis of catalytic systems for the asymmetric oxidation of phenylphenacyl sulfide

Terpene ligands (1S,2S,5S)-3-[{2-[(2-hydroxybenzylidene)amino]ethyl}imino]- 2,6,6-trimethylbicyclo[3.1.1.]heptane-2-ol and 3-({2-[(2-hydroxy-2,6,6- trimethylbicyclo[3.1.1.]hept-3-ilidene)amino]ethyl}imino)-2,6, 6-trimethylbicyclo[3.1.1.]heptane-2-ol have

RuCl2(PPh3)3: A new catalyst for diazocarbonyl insertions into heteroatom-hydrogen bonds

The first ever use of RuCl2(PPh3)3 as a catalyst for diazoketone insertions into heteroatom-hydrogen bonds is described.

Competition Between Cα-S and Cα-Cβ Bond Cleavage in β-Hydroxysulfoxides Cation Radicals Generated by Photoinduced Electron Transfer?

A kinetic and product study of the 3-cyano-N-methyl-quinolinium photoinduced monoelectronic oxidation of a series of β-hydroxysulfoxides has been carried out to investigate the competition between Cα-S and Cα-Cβ bond cleavage within the corresponding cation radicals. Laser flash photolysis experiments unequivocally established the formation of sulfoxide cation radicals showing their absorption band (λmax ≈ 520?nm) and that of 3-CN-NMQ? (λmax ≈ 390?nm). Steady-state photolysis experiments suggest that, in contrast to what previously observed for alkyl phenyl sulfoxide cation radicals that exclusively undergo Cα-S bond cleavage, the presence of a β-hydroxy group makes, in some cases, the Cα-Cβ scission competitive. The factors governing this competition seem to depend on the relative stability of the fragments formed from the two bond scissions. Substitution of the β-OH group with -OMe did not dramatically change the reactivity pattern of the cation radicals thus suggesting that the observed favorable effect of the hydroxy group on the Cα-Cβ bond cleavage mainly resides on its capability to stabilize the carbocation formed upon this scission.

LINKING AMINO ACID SEQUENCES, MANUFACTURING METHOD THEREOF, AND USE THEREOF

This invention provides compositions comprising linked amino acid sequences, pharmaceutical compositions comprising linked amino acid sequences, and methods of making thereof. This invention also provides methods of delivering said compositions to subjects and methods of treating various disorders and diseases using the said compositions.

Air-stable binuclear Titanium(IV) salophen perfluorobutanesulfonate with zinc power catalytic system and its application to C–S and C–Se bond formation

An air-stable μ-oxo-bridged binuclear Lewis acid of titanium(IV) salophen perfluorobutanesulfonate [{Ti(salophen)H2O}2O][OSO2C4F9]2 (1) was successfully synthesized by the reaction of TiIV(salophen)Cl2 with AgOSO2C4F9 and characterized by techniques such as IR, NMR and HRMS. This complex was stable open to air over a year, and exhibited good thermal stability and high solubility in polar organic solvents. The complex also had relatively strong acidity with a strength of 0.8 Ho ≤ 3.3, and showed high catalytic efficiency towards various C–S and C–Se bond formations in the presence of zinc power. This catalytic system affords a mild and efficient approach to synthesis of thio- and selenoesters, α-arylthio- and seleno-carbonyl compounds, and thio- and selenoethers.