162705-20-6Relevant articles and documents
Novel combretastatin analogues effective against murine solid tumors: Design and structure-activity relationships
Ohsumi, Koji,Nakagawa, Ryusuke,Fukuda, Yumiko,Hatanaka, Toshihiro,Morinaga, Yoshihiro,Nihei, Yukio,Ohishi, Kazuo,Suga, Yasuyo,Akiyama, Yukio,Tsuji, Takashi
, p. 3022 - 3032 (2007/10/03)
A series of combretastatin A-4 (CA-4) analogues were synthesized, and their cytotoxic effects against murine Colon 26 adenocarcinoma and inhibitory activity on tubulin polymerization were evaluated. Since CA-4 has limited aqueous solubility, the target co