164172-51-4

Basic information

• Product Name: dimethyl 2-(phenyl(phenylamino)methyl)malonate
• Synonyms: dimethyl 2-(phenyl(phenylamino)methyl)malonate
• CAS NO: 164172-51-4
• Molecular Weight: 313.353
• Mol File: 164172-51-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: dimethyl 2-(phenyl(phenylamino)methyl)malonate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 2-(phenyl(phenylamino)methyl)malonate(164172-51-4)
• EPA Substance Registry System: dimethyl 2-(phenyl(phenylamino)methyl)malonate(164172-51-4)

Safety Data

• Hazardous Substances Data: 164172-51-4(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 62-53-3 aniline 
• 108-59-8 malonic acid dimethyl ester 
• 6626-84-2 dimethyl 2-benzylidenepropanedioate 
• 538-51-2 benzylidene phenylamine 

Relevant articles and documents

Utilization of Solid Acid SO42?/TiO2 as Catalyst to the Three-Component Mannich Reaction at Ambient Temperature

The three-component Mannich reaction of among dimethyl malonate, aromatic primary amine, and aromatic aldehyde was made successfully in the presence of solid acidic catalyst SO42?/TiO2, with excellent catalytic

One-pot synthesis of mannich bases under solvent-free conditions

A mild and practically convenient one-pot procedure for the Mannich reaction via condensation of amines, aldehydes and malonates, β-ketoesters, or β-dicarbonyl compounds has been carried out without using any organic solvent, metallic catalyst, or Lewis acids or bases at room temperature. The present protocol offers several advantages, such as goods yields, simple procedure with easy workup, and the absence of any volatile, hazardous organic solvents and metallic catalyst.