1643979-48-9

Basic information

• Product Name: 3-AMINO-4-PHENYLPYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
• Synonyms: 3-AMINO-4-PHENYLPYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-BOC-TRANS-3-AMINO-4-PHENYL PYRROLIDINE;TERT-BUTYL (3S,4R)-3-AMINO-4-PHENYLPYRROLIDINE-1-CARBOXYLATE
• CAS NO: 1643979-48-9
• Molecular Formula: C15H22N2O2
• Molecular Weight: 262.35
• Mol File: 1643979-48-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-AMINO-4-PHENYLPYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-4-PHENYLPYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(1643979-48-9)
• EPA Substance Registry System: 3-AMINO-4-PHENYLPYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(1643979-48-9)

Safety Data

• Hazardous Substances Data: 1643979-48-9(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1643979-48-9 (rac,trans)-tert-butyl-3-amino-4-phenylpyrrolidine-1-carboxylate 
• 1096341-35-3 trans-1-benzyl-4-phenylpyrrolidin-3-amine 
• 5153-67-3 nitrostyrene 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6

The present disclosure relates to compounds capable of modulating the activity of NR2F6. The compounds of the disclosure may be used in methods for the prevention and/or the treatment of diseases and disorders associated with modulating NR2F6 activity.

N-PYRROLIDINYL, N'-PYRAZOLYL- UREA, THIOUREA, GUANIDINE AND CYANOGUANIDINE COMPOUNDS AS TRKA KINASE INHIBITORS

Compounds of Formula (I) or stereoisomers, tautomers, or pharmaceutically acceptable salts, or solvates or prodrugs thereof, where R1, R2, Ra, Rb, Rc, Rd, X, Ring B, and Ring C are as defined herein, and wherein Ring B and the NH-C(=X)-NH moiety are in the trans configuration, are inhibitors of TrkA kinase and are useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis or pelvic pain syndrome.