164461-16-9

Basic information

• Product Name: methyl (R)-2-acetamido-3-(2-bromophenyl)propanoate
• Synonyms: methyl (R)-2-acetamido-3-(2-bromophenyl)propanoate
• CAS NO: 164461-16-9
• Molecular Weight: 300.152
• Mol File: 164461-16-9.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: methyl (R)-2-acetamido-3-(2-bromophenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (R)-2-acetamido-3-(2-bromophenyl)propanoate(164461-16-9)
• EPA Substance Registry System: methyl (R)-2-acetamido-3-(2-bromophenyl)propanoate(164461-16-9)

Safety Data

• Hazardous Substances Data: 164461-16-9(Hazardous Substances Data)

Upstream product

• 863487-03-0 methyl α-acetamido-β-(2-bromophenyl)-acrylate 
• 461706-35-4 (Z)-4-(2-bromobenzylidene)-2-methyloxazol-5(4H)-one 
• 6630-33-7 ortho-bromobenzaldehyde 
• 194724-01-1 C₁₂H₁₂BrNO₃ 

Relevant articles and documents

A supramolecularly tunable chiral diphosphine ligand: Application to Rh and Ir-catalyzed enantioselective hydrogenation

A supramolecularly tunable chiral bisphosphine ligand bearing two pyridyl-containing crown ethers, (-) or (+)-Xyl-P16C6-Phos, was fabricated and utilized in the Rh-catalyzed asymmetric hydrogenation of α-dehydroamino acid esters and Ir-catalyzed asymmetric hydrogenation of quinolines in high yields with excellent enantioselectivities (90-99% ee). Up to a 22% enhancement in enantioselectivity was achieved by the addition of certain amounts of alkali ions (Li+, Na+ or K+), which could be selectively recognized and effectively complexed by the crown ethers on the chiral Xyl-P16C6-Phos.

Development of robust heterogeneous chiral rhodium catalysts utilizing acid?base and electrostatic interactions for efficient continuous-flow asymmetric hydrogenations

Heterogeneous chiral Rh catalysts based on acid?base and electrostatic interactions have been developed. The robust catalysts demonstrate high activity and selectivity in the continuous-flow asymmetric hydrogenation of a wide variety of enamides and dehyd

Axially chiral electron-rich TunePhos-type ligand: synthesis and applications in asymmetric hydrogenation

A new electron-rich TunePhos type ligand has been synthesized; excellent enantioselectivities (up to 99% ee) have been achieved in Rh-catalyzed asymmetric hydrogenation of α-dehydroamino acid methyl esters and dimethyl itaconate.