164535-25-5

Basic information

• Product Name: 2H-Tetrazole, 5-[4-(bromomethyl)phenyl]-2-(triphenylmethyl)-
• CAS NO: 164535-25-5
• Molecular Formula: C27H21BrN4
• Molecular Weight: 481.395
• Mol File: 164535-25-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2H-Tetrazole, 5-[4-(bromomethyl)phenyl]-2-(triphenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Tetrazole, 5-[4-(bromomethyl)phenyl]-2-(triphenylmethyl)-(164535-25-5)
• EPA Substance Registry System: 2H-Tetrazole, 5-[4-(bromomethyl)phenyl]-2-(triphenylmethyl)-(164535-25-5)

Safety Data

• Hazardous Substances Data: 164535-25-5(Hazardous Substances Data)

Upstream product

• 24994-04-5 5-(4-methylphenyl)-2H-tetrazole 
• 104-85-8 para-methylbenzonitrile 

Downstream Products

• 164535-28-8 2-butyl-1-<<4-<1-(triphenylmethyl)tetrazol-5-yl>phenyl>methyl>-5-formylimidazole 
• 171515-72-3 1-Butyl-5-[1-{2-butyl-3-[4-(2-trityl-2H-tetrazol-5-yl)-benzyl]-3H-imidazol-4-yl}-meth-(Z)-ylidene]-imidazolidine-2,4-dione 
• 171515-73-4 1-Butyl-5-[1-{2-butyl-3-[4-(2-trityl-2H-tetrazol-5-yl)-benzyl]-3H-imidazol-4-yl}-meth-(E)-ylidene]-imidazolidine-2,4-dione 
• 1274939-79-5 Br^(1-)*C₅₃H₄₅N₆O₂⁽¹⁺⁾ 

Relevant articles and documents

Towards non-peptide ANG II AT1 receptor antagonists based on urocanic acid: Rational design, synthesis and biological evaluation

A series of o-, m- and p-benzyl tetrazole derivatives 11a-c has been designed, synthesized and evaluated as potential Angiotensin II AT1 receptor antagonists, based on urocanic acid. Compound 11b with tetrazole moiety at the m-position showed moderate, however, higher activity compared to the o- and p-counterpart analogues. Molecular modelling techniques were performed in order to extract their putative bioactive conformations and explore their binding modes.