1664-35-3

Basic information

• Product Name: ethyl 1-aminocyclopentane-1-carboxylate
• Synonyms: ethyl 1-aminocyclopentane-1-carboxylate hydrochloride;ethyl 1-aminocyclopentane-1-carboxylate;ethyl 1-aminocyclopentanecarboxylate(SALTDATA: HCl);Cyclopentanecarboxylic acid, 1-aMino-, ethyl ester;1-amino-1-cyclopentanecarboxylic acid ethyl ester hydrochloride;1-aminocyclopentane-1-carboxylic acid ethyl ester hydrochloride
• CAS NO: 1664-35-3
• Molecular Formula: C₈H₁₅NO₂
• Molecular Weight: 157.2102
• Mol File: 1664-35-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 207.6 °C at 760 mmHg
• Flash Point: 77.4 °C
• Appearance: /
• Density: 1.056 g/cm³
• Vapor Pressure: 0.223mmHg at 25°C
• Refractive Index: 1.477
• Storage Temp.: 2-8°C(protect from light)
• PKA: 8.27±0.20(Predicted)
• CAS DataBase Reference: ethyl 1-aminocyclopentane-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-aminocyclopentane-1-carboxylate(1664-35-3)
• EPA Substance Registry System: ethyl 1-aminocyclopentane-1-carboxylate(1664-35-3)

Safety Data

• Hazardous Substances Data: 1664-35-3(Hazardous Substances Data)

Usage

General Description

Ethyl 1-aminocyclopentane-1-carboxylate is an organic chemical compound with the molecular formula C8H15NO2. It is an ester derivative of aminocyclopentane carboxylic acid and is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. ethyl 1-aminocyclopentane-1-carboxylate is a colorless liquid with a faint odor and is soluble in organic solvents. It is often used as a reagent in organic synthesis and is known for its mild and selective reactivity. Ethyl 1-aminocyclopentane-1-carboxylate is also found in certain natural products and can be synthesized through various chemical processes.

InChI:InChI=1/C8H15NO2/c1-2-11-7(10)8(9)5-3-4-6-8/h2-6,9H2,1H3

Upstream product

• 52-52-8 1-amino-1-cyclopentanecarboxylic acid 
• 699-51-4 1,3-diazaspiro[4.4]nonane-2,4-dione 
• 76910-12-8 1-Chlorformyl-1-cyclopentancarbonsaeure-ethylester 
• 54378-87-9 1,1-cyclopentanedicarboxylic acid monoethyl ester 
• 4167-77-5 cyclopentane-1,1-dicarboxylic acid diethyl ester 
• 85911-47-3 ethyl N-benzylidene-1-aminocyclopentanecarboxylate 
• 28247-14-5 ethyl 1-cyanocyclopentanecarboxylate 
• 64-17-5 ethanol 

Downstream Products

• 138402-05-8 2-butyl-1,3-diaza-spiro[4.4]non-1-en-4one 
• 138402-10-5 trityl irbesartan 
• 13909-05-2 1-({[(2-chloroethyl)nitrosoamino]carbonyl}amino)-cyclopentanecarboxylic acid, ethyl ester 
• 76910-15-1 1,1'-<(5-Nitro-4,6-pyrimidindiyl)diamino>-1,1'-dicyclopentanmethanol 
• 151257-05-5 tert-butyl-4'-<(2-n-butyl-4-oxo-1,3-diazaspiro<4.4>non-2-en-1-yl)methyl>biphenyl-2-carboxylate 
• 138402-11-6 2-butyl-3-{4-[2-(1H-tetrazol-5-yl)phenyl]benzyl}-1,3-diazaspiro[4.4]non-1-en-4-one 
• 151257-04-4 tert-butyl-4'-<(2-n-butyl-4-oxo-1,3-diazaspiro<4.4>nonan-1-yl)methyl>biphenyl-2-carboxylate 
• 151257-08-8 tert-butyl-4'-<(2-n-butyl-4-oxo-1,3-diazaspiro<4.4>nonan-3-yl)methyl>biphenyl-2-carboxylate 
• 138401-34-0 tert-butyl-4'-<(2-n-butyl-4-thioxo-1,3-diazaspiro<4.4>non-1-en-3-yl)methyl>biphenyl-2-carboxylate 
• 138401-20-4 tert-butyl-4'-<(2-n-butyl-4-oxo-1,3-diazaspiro<4.4>non-1-en-3-yl)methyl>biphenyl-2-carboxylate 
• 138401-24-8 4'-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1'-biphenyl]-2-carbonitrile 
• 151257-03-3 2-n-butyl-1,3-diazaspiro<4.4>nonan-4-one 
• 115572-39-9 1-((S)-2-{[(S)-1-(2-Benzyloxycarbonylamino-acetyl)-pyrrolidine-2-carbonyl]-amino}-propionylamino)-cyclopentanecarboxylic acid ethyl ester 
• 75230-15-8 1-[(Z)-2,3-Dibromo-4,4-bis-(4-ethyl-phenyl)-but-2-enoylamino]-cyclopentanecarboxylic acid ethyl ester 

Relevant articles and documents

NOVEL DUAL ACTION RECEPTORS ANTAGONISTS (DARA) AT THE AT1 AND ETA RECEPTORS

The present invention relates to new compounds of the formula [Chemical formula should be inserted here. Please see paper copy] wherein R1, R2, R3, and R31 are as specified herein. The invention also relates to a method for preparation thereof, as well as combinations of the new compounds with previously known agents. The invention also relates to the use of the above-mentioned compounds and combinations for the preparation of a medicament for treating hypertension of different kinds, alleviating organ damage of different kinds, treating or preventing diabetic nephropathy, treating endothelin and angiotensin mediated disorders, and treating prostate cancer.

Therapeutic agents

Compounds of formula I STR1 and pharmaceutically acceptable salts thereof in which m is an integer from 1 to 3; n is an integer from 2 to 6; R1 is phenyl optionally substituted by one or more substituents selected from halo, hydroxy, alkoxy, alkanoyl, alkyl, halogenated alkyl, alkylthio, alkylsulphinyl, alkylsulphonyl, cyano, nitro, optionally substituted amino, optionally substituted sulphamoyl, optionally substituted carbamoyl or phenyl, or R1 is naphthyl; R2 is H, alkyl or phenyl; R3 is H, alkyl, alkenyl or alkoxyalkyl; R4 is H or hydroxy; and R5 is H or together with R4 represents a bond; have utility in the treatment of obesity and affective disorders such as depression and anxiety.

Peptide derivatives and processes for their preparation

Peptide ester and amide derivatives of the general formula I: STR1 in which X is H or an acyl, A and B are structurally defined amino acid residues, n is an integer of from 1 to 3, R1 is H or a lower alkyl and either R2 or C is a def