167889-18-1

Basic information

• Product Name: N-[2-(1-Azabicyclo[3.3.0]octan-5-yl)ethyl]-2-nitroaniline fumarate
• Synonyms: SK-946; 2-nitro-N-[2-(tetrahydro-1H-pyrrolizin-7a(5H)-yl)ethyl]aniline (2E)-but-2-enedioate
• CAS NO: 167889-18-1
• Molecular Formula: C₁₉H₂₅N₃O₆
• Molecular Weight: 391.4183
• Mol File: 167889-18-1.mol

Chemical Properties

• Boiling Point: 421.7°C at 760 mmHg
• Flash Point: 208.9°C
• Vapor Pressure: 2.55E-07mmHg at 25°C
• CAS DataBase Reference: N-[2-(1-Azabicyclo[3.3.0]octan-5-yl)ethyl]-2-nitroaniline fumarate(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(1-Azabicyclo[3.3.0]octan-5-yl)ethyl]-2-nitroaniline fumarate(167889-18-1)
• EPA Substance Registry System: N-[2-(1-Azabicyclo[3.3.0]octan-5-yl)ethyl]-2-nitroaniline fumarate(167889-18-1)

Safety Data

• Hazardous Substances Data: 167889-18-1(Hazardous Substances Data)

Relevant articles and documents

Compounds and use thereof

There is disclosed a compound shown by a formula of STR1 wherein R 1 is a hydrogen atom alkyl group having 1-4 carbon atoms or acyl group having 1-4 carbon atoms: R 2 and R 3 are a hydrogen atom, alkyl group having 1-4 carbon atoms, phenyl radical, halogen atom, cyano radical, acyl group having 1-4 carbon atoms, nitro radical, alkoxy group having 1 or 2 carbon atoms, or substituted or non-substituted amino group, respectively; n is an integer of 1-3; and dotted line means a possible ring, and a salt thereof. The compound and salt bind with muscarinic receptor in brain to develop a powerful actuation thereof and thus those can be used as an effective ingredient for preventing and curing senile dementias, and more particularly Alzheimer''s disease.