170098-21-2

Basic information

• Product Name: 2-TERT-BUTYLTHIOBENZAMIDE
• Synonyms: 2-TERT-BUTYLTHIOBENZAMIDE;2-tert-butylsulfanylbenzamide
• CAS NO: 170098-21-2
• Molecular Formula: C11H15NS
• Molecular Weight: 193.3085
• Mol File: 170098-21-2.mol

Chemical Properties

• Boiling Point: 340.0±25.0 °C(Predicted)
• Appearance: /
• Density: 1.11±0.1 g/cm3(Predicted)
• PKA: 15.67±0.50(Predicted)
• CAS DataBase Reference: 2-TERT-BUTYLTHIOBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-TERT-BUTYLTHIOBENZAMIDE(170098-21-2)
• EPA Substance Registry System: 2-TERT-BUTYLTHIOBENZAMIDE(170098-21-2)

Safety Data

• Hazardous Substances Data: 170098-21-2(Hazardous Substances Data)

Upstream product

• 394-47-8 2-fluorobenzonitrile 
• 184169-45-7 2-(tert-butylthio)benzonitrile 
• 75-66-1 2-methylpropan-2-thiol 

Relevant articles and documents

Synthesis method of drug for treating diabetes

The invention relates to the fields of organic synthesis and pharmacy, and particularly relates to a synthesis method of a drug for treating diabetes. The synthesis method comprises the following steps of (1), hydrolyzing 2-cyanophenyl tert-butyl sulfide to produce o-carbamoylphenyl tert-butyl sulfide; (2), oxidizing the o-carbamoylphenyl tert-butyl sulfide to produce o-carbamoylphenyl tert-butylsulfoxide; (3), enabling the o-carbamoylphenyl tert-butyl sulfoxide to generate an intramolecular multicomponent reaction with phenyl isocyanide to produce 2-(aniline)-4H-benzo[e][1,3]thiazin-4-one. The synthesis method is simple, convenient and environmentally friendly, is easy to operate and suitable for industrialized production, and is low in cost and high in yield; synthesis raw materials areeasily obtained, and the atom economy is achieved.

Thermolysis-Induced Two- or Multicomponent Tandem Reactions Involving Isocyanides and Sulfenic-Acid-Generating Sulfoxides: Access to Diverse Sulfur-Containing Functional Scaffolds

Direct reaction of isocyanides with some sulfenic-acid-generating sulfoxides led to the effective formation of the corresponding thiocarbamic acid S-esters in good to high yields. A multicomponent reaction involving isocyanide, sulfoxide, and a suitable nucleophile has also been developed, providing ready access to a diverse range of sulfur-containing compounds, including isothioureas, carbonimidothioic acid esters, and carboximidothioic acid esters.

Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones

A method for producing an alkylthiobenzamide by carrying out a reaction of a halobenzamide with an alkanethiol in the presence of a base in a heterogeneous solvent; a method for producing an alkylsulfinylbenzamide by carrying out a reaction of an alkylthi