171050-08-1

Basic information

• Product Name: N-[[2-cyano-4-t-butoxycarbonyl]phenyl]-L-aspartic acid β-methyl ester
• Synonyms: N-[[2-cyano-4-t-butoxycarbonyl]phenyl]-L-aspartic acid β-methyl ester
• CAS NO: 171050-08-1
• Molecular Weight: 348.356
• Mol File: 171050-08-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-[[2-cyano-4-t-butoxycarbonyl]phenyl]-L-aspartic acid β-methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-[[2-cyano-4-t-butoxycarbonyl]phenyl]-L-aspartic acid β-methyl ester(171050-08-1)
• EPA Substance Registry System: N-[[2-cyano-4-t-butoxycarbonyl]phenyl]-L-aspartic acid β-methyl ester(171050-08-1)

Safety Data

• Hazardous Substances Data: 171050-08-1(Hazardous Substances Data)

Upstream product

• 2177-62-0 β-methyl L-aspartate 
• 171050-07-0 t-butyl 4-fluoro-3-cyanobenzoate 
• 171050-06-9 3-cyano-4-fluorobenzoic acid 
• 179897-89-3 5-Bromo-2-fluoro-benzonitrile 

Downstream Products

• 171050-09-2 N-[[2-formyl-4-t-butoxycarbonyl]phenyl]-L-aspartic acid β-methyl ester 

Relevant articles and documents

An Alternate Enantiospecific Synthesis of Methyl (S)-7-tert-Butoxycarbonyl-2,3,4,5-Tetrahydro-4-Methyl-3-Oxo-1H-1,4-Benzodiazepine-2-Acetate

An alternate enantiospecific synthesis of methyl (S)-7-tert-butoxycarbonyl-2,3,4,5-tetrahydro-4-methyl-3-oxo-1H-1,4-benzodiazepine-2-acetate (5) is reported.The key step, which involves an intermolecular displacement of the activated aryl fluoride (9) by L-aspartic acid β-mehtyl ester, proceeds without racemization.