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Cas Database

17179-91-8

17179-91-8

Identification

Synonyms:monomethyl 3-methylglutaric acid;2,4-dimethypentane;Pentane,2,4-dimethyl;Diisopropylmethane;3,4-Dimethylglutaric acid;2,3-Dimethyl-glutarsaeure;2,3-dimethylglutaric acid;2,4-dimethyl pentane;

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Safety information and MSDS view more

  • Signal Word:Warning

  • Hazard Statement:H319 Causes serious eye irritation

  • First-aid measures: General adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

  • Fire-fighting measures: Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.

  • Accidental release measures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

  • Handling and storage: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

  • Exposure controls/personal protection:Occupational Exposure limit valuesBiological limit values Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/face protection Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Respiratory protection Wear dust mask when handling large quantities. Thermal hazards

Supplier and reference price view more

  • Manufacture/Brand
  • Product Description
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  • Manufacture/Brand:TRC
  • Product Description:2,3-DIMETHYLGLUTARIC ACID
  • Packaging:10mg
  • Price:$ 45
  • Delivery:In stock
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  • Manufacture/Brand:TRC
  • Product Description:2,3-DIMETHYLGLUTARIC ACID
  • Packaging:100mg
  • Price:$ 175
  • Delivery:In stock
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  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:2,3-DIMETHYLGLUTARIC ACID Aldrich
  • Packaging:1g
  • Price:$ 144
  • Delivery:In stock
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  • Manufacture/Brand:American Custom Chemicals Corporation
  • Product Description:2,3-DIMETHYLGLUTARIC ACID 95.00%
  • Packaging:1G
  • Price:$ 626.43
  • Delivery:In stock
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Relevant articles and documentsAll total 3 Articles be found

Urea compounds as inhibitors for vla-4

-

, (2008/06/13)

A compound of formula (I) where D is a VLA-4 specificity determinant which does not impart significant IIB/IIIa activity; R41 is a group of the formula (V): U - (CH2)d - V - T wherein U is selected from oxygen, sulphur, a direct bond or —CH2O—, V is selected from nitrogen, oxygen, sulphur, S(O), S(O)2 or a direct bond, d is zero or a number from 1 to 4, and T is selected from a range of variables defined in the application; and other variables are defined in the application, or a pharmaceutically acceptable salt or in vivo hydrolysable derivative thereof. The compounds are useful in the treatment of disease mediated by the interaction between VCAM-1 and/or fibronectin and the integrin receptor α4β1. Pharmaceutical compositions and methods of use or treatment are also described and claimed.

A DIASTEREO- AND ENANTIOSELECTIVE MICHAEL ADDITION OF CHIRAL AMIDE ENOLATES TO α,β-UNSATURATED ESTERS; A STEREOSELECTIVE SYNTHESIS OF (+)-DEHYDROIRIDODIOL AND (-)-ISODEHYDROIRIDODIOL

Yamaguchi, Masahiko,Hasebe, Koichi,Tanaka, Shinya,Minami, Toru

, p. 959 - 962 (2007/10/02)

(+)-Dehydroiridodiol and (-)-isodehydroiridodiol were synthesized stereoselecticely using the diastereo- and enantioselective Michael addition of chiral amide enolates to α,β-unsaturated esters.

Process route upstream and downstream products

Process route

3,4-Dimethylglutaric acid
17179-91-8

3,4-Dimethylglutaric acid

Conditions
Conditions Yield
With hydrogenchloride; (fluessige Form) Abtrennen des gleichzeitig entstandenen 2.3-Dimethyl-glutarsaeure-imids und Verseifen mit Alkalilauge;
2-methyl-butane-1,3,3-tricarboxylic acid
858834-81-8

2-methyl-butane-1,3,3-tricarboxylic acid

3,4-Dimethylglutaric acid
17179-91-8

3,4-Dimethylglutaric acid

Conditions
Conditions Yield
Die beiden (H 678,679) beschriebenen stereoisomeren Formen bilden sich nebeneinander; bei der Destillation; Trennung durch Ueberfuehren der festen Form in das Imid;
3,3-Dimethyl-2-methylen-cyclohexen-<sup>(6)</sup>-al-<sup>(1)</sup>, Pironen-aldehyd
81054-01-5

3,3-Dimethyl-2-methylen-cyclohexen-(6)-al-(1), Pironen-aldehyd

3,4-Dimethylglutaric acid
17179-91-8

3,4-Dimethylglutaric acid

Conditions
Conditions Yield
With potassium permanganate; In water;
3,4-Dimethylglutaric acid
17179-91-8

3,4-Dimethylglutaric acid

Conditions
Conditions Yield
at 145 ℃; cis-α.β-dimethyl-glutaric acid; zur Reinigung wird die Saeure in den Aethylester verwandelt und dieser wieder verseift;
3,4-Dimethylglutaric acid
17179-91-8

3,4-Dimethylglutaric acid

Conditions
Conditions Yield
With sulfuric acid; cis-α.β-dimethyl-glutaric acid; Hydrolysis;
2-hydroxy-2,3-dimethyl-glutaric acid
876504-08-4

2-hydroxy-2,3-dimethyl-glutaric acid

3,4-Dimethylglutaric acid
17179-91-8

3,4-Dimethylglutaric acid

Conditions
Conditions Yield
With hydrogen iodide; trans-α.β-dimethyl-glutaric acid;
potassium cyanide
151-50-8

potassium cyanide

3,4-Dimethylglutaric acid
17179-91-8

3,4-Dimethylglutaric acid

Conditions
Conditions Yield
at 270 - 280 ℃; cis-α.β-dimethyl-glutaric acid; Durch Verseifen der gebildeten Nitrilsaeure;
2-cyano-2,3-dimethyl-glutaric acid
903639-00-9

2-cyano-2,3-dimethyl-glutaric acid

3,4-Dimethylglutaric acid
17179-91-8

3,4-Dimethylglutaric acid

Conditions
Conditions Yield
With hydrogenchloride; trans-α.β-dimethyl-glutaric acid;
3,4-Dimethyl-5-oxo-5-pyrrolidin-1-yl-pentanoic acid ethyl ester

3,4-Dimethyl-5-oxo-5-pyrrolidin-1-yl-pentanoic acid ethyl ester

(2RS,3SR)-2,3-Dimethylpentanedioic acid
17179-91-8,76075-59-7,107932-91-2,107983-87-9,107983-88-0

(2RS,3SR)-2,3-Dimethylpentanedioic acid

(2RS,3RS)-2,3-Dimethylpentanedioic acid

(2RS,3RS)-2,3-Dimethylpentanedioic acid

Conditions
Conditions Yield
With hydrogenchloride; for 7h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Heating;
crotonic acid methyl ester
623-43-8

crotonic acid methyl ester

(S)-(-)-prolinol propionamide
74036-66-1

(S)-(-)-prolinol propionamide

(2S,3R)-2,3-Dimethyl-pentanedioic acid
17179-91-8,76075-59-7,107932-91-2,107983-87-9,107983-88-0

(2S,3R)-2,3-Dimethyl-pentanedioic acid

(2S,3S)-2,3-Dimethyl-pentanedioic acid
17179-91-8,76075-59-7,107932-91-2,107983-87-9,107983-88-0

(2S,3S)-2,3-Dimethyl-pentanedioic acid

erythro-2,3-dimethylglutaric acid
107983-88-0

erythro-2,3-dimethylglutaric acid

threo-2,3-dimethylglutaric acid
107983-87-9

threo-2,3-dimethylglutaric acid

Conditions
Conditions Yield
With hydrogenchloride; lithium diisopropyl amide; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1.) THF, -78 deg C, 2.) reflux, 2 h;

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