17180-62-0

Basic information

• Product Name: Methanone, (3-methyloxiranyl)phenyl-
• CAS NO: 17180-62-0
• Molecular Formula: C10H10O2
• Molecular Weight: 162.188
• Mol File: 17180-62-0.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Methanone, (3-methyloxiranyl)phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (3-methyloxiranyl)phenyl-(17180-62-0)
• EPA Substance Registry System: Methanone, (3-methyloxiranyl)phenyl-(17180-62-0)

Safety Data

• Hazardous Substances Data: 17180-62-0(Hazardous Substances Data)

Upstream product

• 35660-91-4 (E)-1-phenyl-2-buten-1-one 
• 35660-91-4 (Z)-1-phenylbut-2-en-1-one 
• 75-07-0 acetaldehyde 
• 70-11-1 α-bromoacetophenone 
• 121788-93-0 3-Chlor-1-phenyl-2-(trimethylsiloxy)-1-butanon 
• 10133-06-9 methyl (+/-)-trans-(2,3)-epoxy butanoate 
• 591-51-5 phenyllithium 
• 5623-21-2 α-allylbenzoin 
• 532-27-4 1-chloroacetophenone 
• 52755-38-1 1-phenyl-2-buten-1-ol 
• 495-41-0 1-phenylbut-2-en-1-one 

Downstream Products

• 1422017-20-6 N-((3-methyloxiran-2-yl)(phenyl)methylene)-2-phenylaziridin-1-amine 
• 61752-45-2 Z-1-phenylpent-3-en-1-one 
• 74157-93-0 trans-1-phenyl-3-penten-1-one 
• 1210039-68-1 C₁₁H₁₂⁽²⁾H₂O₂ 
• 3457-55-4 1-phenyl-1,2-butanedione 
• 283166-69-8 3-hydroxy-2-(hydroxy-phenyl-methyl)-1-phenyl-butan-1-one 
• 13505-39-0 3-hydroxy-1-phenyl-butan-1-one 
• 2408-88-0 2-benzylsulfanyl-1-phenylethanone 
• 21875-71-8 Decylphenacylsulfid 

Relevant articles and documents

Benchtop-Stabssle Hypervalent Bromine(III) Compounds: Versatile Strategy and Platform for Air- And Moisture-Stable λ3-Bromanes

We present the first synthesis of air/moisture-stable λ3-bromanes (9and10) by using a cyclic 1,2-benzbromoxol-3-one (BBX) strategy. X-ray crystallography and NMR and IR spectroscopy ofN-triflylimino-λ3-bromane (12) revealed that the bromine(III) center is effectively stabilized by intramolecular R-Br-O hypervalent bonding. This strategy enables the synthesis of a variety of air-, moisture-, and benchtop-stable Br-hydroxy, -acetoxy, -alkynyl, -aryl, and bis[(trifluoromethyl)sulfonyl]methylide λ3-bromane derivatives.

Convenient methods for the preparation of unsymmetrical double aldols

Double aldol reaction proceeded stereoselectively at one α-carbon of ketones to give α-(1-hydroxyalkyl)-β-hydroxyalkyl ketones (double aldols) in good to high yields by the following three methods: i) tin(II) trifluoromethanesulfonate-mediated aldol reaction of aldehydes with β-hydroxy ketones (mono-aldols) in the presence of tertiary amines, ii) samarium(II) iodide-mediated aldol reaction of aldehydes with alkyl or aryl oxiranyl ketones, iii) Sn(OTf)2- promoted aldol reaction of α-bromo ketones with aldehydes giving α-bromo-β-stannyloxy ketones which were then converted to titanium enolates on treatment with low-valent titanium. Double aldols were formed by subsequent reaction of the above titanium enolates with aldehydes in one-pot procedure. Further, small and medium-sized carbocyclic compounds whose ring skeletons were composed of double aldol structure were synthesized by SmI2-mediated intramolecular cyclization between oxiranyl ketone and aldehyde functions.

The first catalytic enantioselective synthesis of cis-epoxyketones from cis-enones

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