17257-79-3

Basic information

• Product Name: 2β-Acetyl-3α-methyloxirane
• Synonyms: 2β-Acetyl-3α-methyloxirane;1-(3-Methyloxiranyl)ethanone
• CAS NO: 17257-79-3
• Molecular Formula: C₅H₈O₂
• Molecular Weight: 100.1158
• Mol File: 17257-79-3.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 135.4°Cat760mmHg
• Flash Point: 37.3°C
• Appearance: /
• Density: 1.048g/cm³
• Vapor Pressure: 7.74mmHg at 25°C
• Refractive Index: 1.431
• CAS DataBase Reference: 2β-Acetyl-3α-methyloxirane(CAS DataBase Reference)
• NIST Chemistry Reference: 2β-Acetyl-3α-methyloxirane(17257-79-3)
• EPA Substance Registry System: 2β-Acetyl-3α-methyloxirane(17257-79-3)

Safety Data

• Hazardous Substances Data: 17257-79-3(Hazardous Substances Data)

Usage

Uses

3,4-Epoxy-2-pentanone is a starting material to prepare chiral peroxides as biologically interesting or even clinically important compounds.

InChI:InChI=1/C5H8O2/c1-3(6)5-4(2)7-5/h4-5H,1-2H3

Upstream product

• 103144-67-8 trans-3-methyl-2-acetyloxirane diethylketal 
• 3102-33-8 trans-3-penten-2-one 
• 88339-92-8 C₁₁H₂₀HgO₅ 
• 625-33-2 3-penten-2-one 
• 80-15-9 Cumene hydroperoxide 
• 75-91-2 tert.-butylhydroperoxide 
• 3102-32-7 (Z)-3-penten-2-one 

Downstream Products

• 3102-33-8 trans-3-penten-2-one 
• 123-54-6 acetylacetone 
• 103144-77-0 trans-3-methyl-2-acetylthiirane 
• 105827-07-4 C₂₉H₃₉Cl₃O₉ 
• 6334-18-5 2,3-dichlorobenzylaldehyde 
• 83750-10-1 1-((4R,5R)-2,4-Dimethyl-4,5-dihydro-oxazol-5-yl)-ethanone 
• 600-14-6 2,3-Pentanedione 
• 67-56-1 methanol 
• 702651-39-6 (E)-3-Dimethylamino-1-(3-methyl-oxiranyl)-propenone 
• 71808-93-0 (Z)-3-Thiocyanato-pent-3-en-2-one 
• 101420-60-4 3,4-dihydroxy-pentan-2-one 
• 100061-91-4 3,4-epoxy-pentan-2-one-(2,4-dinitro-phenylhydrazone) 

Relevant articles and documents

Iron-Catalyzed Epoxidation of Linear α-Olefins with Hydrogen Peroxide

The combination of Fe(OTf)2 with N-methyl bis(picolylamine) (Me-bpa) L7 enables epoxidation of linear olefins including terminal, internal, and cyclic ones, using hydrogen peroxide as terminal oxidant under mild conditions. In the presence of picolinic acid as additive improved yields of epoxides up to 75 % have been achieved.

Facile epoxidation of α,β-unsaturated ketones with cyclohexylidenebishydroperoxide

Cyclohexylidenebishydroperoxide was successfully used as the oxygen source for the oxidation of α,β-unsaturated ketones for the first time. The corresponding epoxides were obtained in excellent yields under the Weitz-Scheffer reaction conditions.

TRANSFORMATION OF ACETYLOXIRANES TO THIIRANE ANALOGS

A method for the synthesis of acetylthiiranes was developed; this method includes the conversion of acetyloxiranes to diethylketals, dealkoxylation of the latter, replacement of the oxygen atom of the oxirane ring by sulfur, and acidic hydrolysis of the ethoxyvinylthiirane to acetylthiiranes.