172900-75-3

Basic information

• Product Name: Benzaldehyde, 4-methoxy-3-(3-methoxypropoxy)-
• Synonyms: Benzaldehyde, 4-methoxy-3-(3-methoxypropoxy)-;3-(3-methoxypropoxy)-4-methoxybenzaldehyde;4-Methoxy-3-(3-Methoxypropoxy)benzaldehyde;172900-75-3
• CAS NO: 172900-75-3
• Molecular Formula: C₁₂H₁₆O₄
• Molecular Weight: 224.25304
• Product Categories: Drug Intermediates;aliskiren
• Mol File: 172900-75-3.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 341.9 °C at 760 mmHg
• Flash Point: 150.2 °C
• Appearance: /
• Density: 1.093 g/cm³
• Vapor Pressure: 7.8E-05mmHg at 25°C
• Refractive Index: 1.516
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Benzaldehyde, 4-methoxy-3-(3-methoxypropoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 4-methoxy-3-(3-methoxypropoxy)-(172900-75-3)
• EPA Substance Registry System: Benzaldehyde, 4-methoxy-3-(3-methoxypropoxy)-(172900-75-3)

Safety Data

• Hazardous Substances Data: 172900-75-3(Hazardous Substances Data)

Usage

General Description

Benzaldehyde, 4-methoxy-3-(3-methoxypropoxy)- is a chemical compound with a molecular formula of C17H20O4. It is a fragrant liquid that belongs to the class of organic compounds known as methoxyphenols. It is commonly used as a raw material for the synthesis of various pharmaceuticals, flavors, and fragrances. Its aromatic properties make it a popular ingredient in perfumes and flavorings, and it has also been studied for its potential antimicrobial and antioxidant properties. This chemical is mainly produced through synthetic methods and is not typically found in nature.

InChI:InChI=1/C12H16O4/c1-14-6-3-7-16-12-8-10(9-13)4-5-11(12)15-2/h4-5,8-9H,3,6-7H2,1-2H3

Upstream product

• 67-56-1 methanol 
• 148433-01-6 3-(3-bromopropoxy)-4-methoxybenzaldehyde 
• 621-59-0 isovanillin 
• 1589-49-7 methoxypropanol 
• 124-41-4 sodium methylate 
• 36865-41-5 3-bromopropanol methyl ether 
• 127686-58-2 3-Methoxy-1-propanol methanesulphonate 

Downstream Products

• 172900-74-2 [4-methoxy-3-(3-methoxypropoxy)-phenyl]methanol 
• 1351987-44-4 C₁₈H₂₈O₆ 
• 1097998-77-0 2-[1-[4-methoxy-3-(3-methoxypropoxy)phenyl]meth-(E)-ylidene]-3-methylbutyraldehyde 
• 1097998-75-8 2-[1-[4-methoxy-3-(3-methoxypropoxy)phenyl]meth-(Z)-ylidene]-3-methylbutyraldehyde 
• 387356-93-6 ethyl syn-2-(4-methoxy-3-(3-methoxypropoxy)benzylidene)-3-methylbutanoate 
• 387356-93-6 ethyl anti-2-(4-methoxy-3-(3-methoxypropoxy)benzylidene)-3-methylbutanoate 
• 1524157-76-3 (E)-3-(4-methoxy-3-(3-methoxypropoxy)phenyl)-2-methylprop-2-en-1-ol 
• 324763-47-5 (2S,4S,5S,7S)-N-(3-amino-2,2-dimethyl-3-oxopropyl)-5-azido-4-hydroxy-2-isopropyl-7-(4-methoxy-3-(methoxypropoxy)benzyl)-8-methylnonanamide 
• 387353-75-5 4-Bromo-benzenesulfonic acid (1R,3S)-1-((2S,4S)-4-isopropyl-5-oxo-tetrahydro-furan-2-yl)-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl ester 
• 324763-46-4 (3S,5S)-5-{(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl}-dihydro-3-(1-methylethyl)furan-2(3H)-one 
• 325740-67-8 (3S,5S)-dihydro-5-{(1S,3S)-1-hydroxy-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl}-3-(1-methylethyl)furan-2(3H)-one 
• 324763-45-3 (3S,5S)-5-{(1R,3S)-1-Hydroxy-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-3-isopropyl-dihydro-furan-2-one 
• 324763-38-4 N-(2-hydroxy-1-methyl-2-phenyl-ethyl)-2-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-3,N-dimethyl-butyramide 
• 324763-37-3 N-(2-hydroxy-1-methyl-2-phenyl-ethyl)-3-[4-methoxy-3-(3-methoxy-propoxy)-phenyl]-N-methyl-propionamide 

Relevant articles and documents

HEPATITIS B VIRUS SURFACE ANTIGEN INHIBITOR

Disclosed in the present invention is a new 11-oxo-7,11-dihydro-6h-benzo-[f]pyrido[1,2-d][1,4]azepine oxepin-10-carboxylic acid derivative serving as a hepatitis B virus surface antigen inhibitor. Specifically disclosed are a compound represented by formula (V) or a pharmaceutically acceptable salt thereof, and applications of the compound represented by formula (V) or the pharmaceutically acceptable salt thereof and a pharmaceutical composition thereof in the treatment of viral hepatitis B.

DIHYDROQUINOLIZINONES AS ANTIVIRALS

Compounds, specifically hepatitis B virus and/or hepatitis D virus inhibitors, more specifically compounds that inhibit HBe antigen and HBs antigen in a subject, for the treatment of viral infections, and methods of preparing and using such compounds. Formula (I):

An improved and economical process for the manufacture of the key intermediate of aliskiren, a new potent renin inhibitor

An improved, practical, economical and efficient process for the production of (2S,4S)-2-amino-4-(4-methoxy-3-(3-methoxypropoxy)benzyl)-5-methylhexanoic acid, a key intermediate of the new potent renin inhibitor of aliskiren, in a total yield over 30% is described. This process avoids expensive reagents and chromatographic purifications, and is easily scaled up in industry.