173156-86-0Relevant articles and documents
Composition containing at least one bicyclic aromatic compound and at least one lipophilic sunscreen, and uses thereof
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, (2008/06/13)
A composition containing at least one lipophilic sunscreen and at least one bicyclic aromatic compound represented by formula (I): or a salt or chiral analogue of such a compound, where the structural variables R1, Ar, X, R2 Y and X are defined herein, and at least one lipophilic sunscreen.
RXR-agonist polycyclic aromatic compounds, pharmaceutical/cosmetic compositions comprising said compound and uses thereof
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, (2008/06/13)
Novel pharmaceutically/cosmetically-active polycyclic aromatic compounds having the structural formula (I): wherein Ar is a radical having one of the formulae (a)-(e): which are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders are provided. In particular, based on their RXR-agonist activity, these compounds may be used to treat noninsulin-dependent diabetes mellitus (NIDDM) and obesity.
Synthesis and structure-activity relationships of retinoid X receptor selective diaryl sulfide analogs of retinoic acid
Beard, Richard L.,Colon, Diana F.,Song, Tae K.,Davies, Peter J. A.,Kochhar, Devendra M.,Chandraratna, Roshantha A. S.
, p. 3556 - 3563 (2007/10/03)
Retinoids exert their biological effects by binding to and activating nuclear receptors that interact with responsive elements on DNA to promote gene transcription. There are two families of retinoid receptors, the retinoic acid receptor (RAR) family and