174184-13-5

Basic information

• Product Name: 1-Piperidinecarboxylic acid, 3-broMo-4-oxo-, phenylMethyl ester
• Synonyms: 1-Piperidinecarboxylic acid, 3-broMo-4-oxo-, phenylMethyl ester;Benzyl 3-bromo-4-oxopiperidine-1-carboxylate;3-Bromo-4-oxo-piperidine-1-carboxylicacidbenzylester;1-Cbz-3-bromo-4-oxo-piperidine
• CAS NO: 174184-13-5
• Molecular Formula: C₁₃H₁₄BrNO₃
• Molecular Weight: 312.15916
• Mol File: 174184-13-5.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 423.7±45.0 °C(Predicted)
• Appearance: /
• Density: 1.510±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: -3.40±0.40(Predicted)
• CAS DataBase Reference: 1-Piperidinecarboxylic acid, 3-broMo-4-oxo-, phenylMethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidinecarboxylic acid, 3-broMo-4-oxo-, phenylMethyl ester(174184-13-5)
• EPA Substance Registry System: 1-Piperidinecarboxylic acid, 3-broMo-4-oxo-, phenylMethyl ester(174184-13-5)

Safety Data

• Hazardous Substances Data: 174184-13-5(Hazardous Substances Data)

Usage

General Description

1-Piperidinecarboxylic acid, 3-brom-4-oxo-, phenylmethyl ester, also known as Phenibut, is a derivative of GABA, a neurotransmitter in the brain that helps to regulate anxiety and mood. It is a psychoactive drug that is commonly used as a nootropic, or cognitive enhancer, due to its ability to reduce stress and improve cognitive function. Phenibut has been used to treat anxiety, insomnia, and other mood disorders, but it can also be habit-forming and has the potential for abuse. It is important to use this chemical under the guidance of a healthcare professional to avoid potential side effects and dependence.

Upstream product

• 19099-93-5 benzyl 4-oxo-1-piperidinecarboxylate 

Downstream Products

• 853784-25-5 2-(4-fluorophenyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine 
• 1030122-16-7 2-methyl-4,5,6,7-tetrahydro-thiazolo(5,4-c)pyridinium bromide 
• 1186688-44-7 benzyl 3-hydroxy-4,4-dimethoxypiperidine-1-carboxylate 
• 1030012-81-7 benzyl 2-methyl-6,7-dihydro-4H-thiazolo[5,4-c]pyridine-5-carboxylate 
• 901309-20-4 benzyl 2-(2-(2-tert-butylphenoxy)pyridin-3-ylamino)-6,7-dihydrothiazolo-[5,4-c]pyridine-5(4H)-carboxylate 
• 733758-00-4 2-(4-methanesulfonyl-phenyl)-6,7-dihydro-4H-thiazolo[5,4-c]pyridine-5-carboxylic acid benzyl ester 
• 733757-97-6 2-(4-methanesulfonyl-phenyl)-4,5,6,7-tetrahydro-thiazolo[5,4-c]pyridine 
• 853784-26-6 2-(4-methylsulfanyl-phenyl)-4,5,6,7-tetrahydro-thiazolo[5,4-c]pyridine 
• 733757-99-8 2-(4-methylsulfanyl-phenyl)-6,7-dihydro-4H-thiazolo[5,4-c]pyridine-5-carboxylic acid benzyl ester 
• 1354910-20-5 2-(4-methoxy-phenyl)-6,7-dihydro-4H-thiazolo[5,4-c]pyridine-5-carboxylic acid benzyl ester 

Relevant articles and documents

CHEMICAL COMPOUNDS AS ANTIBIOTICS

The invention relates to a compound which is an indane derivative according to Formula (I), or a pharmaceutically acceptable salt thereof, [FORMULA (I)] wherein R1, R2, R3, n, R4, p? q, L, ?, X and m are as defined herein. The compounds are useful in the treatment of antibacterial infection either as stand alone antibiotics, or in combination with further antibiotics. The compounds can also be used in vitro, for example in cleaning compositions.

PRMT5 INHIBITORS AND USES THEREOF

Described herein are compounds of Formula (A), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof:wherein Y1 is of formula (?) or formula (y):Ring Y is a 5- to 6-membered heteroaryl ring; and V4, V5, Rx, x, y, and n are as defined herein. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.

ALKYLAMINOPYRIDINE DERIVATIVE

The present invention relates to a compound that is useful for treatment of, for example, hypertension, arteriosclerosis, bulimia and obesity because of having an antagonistic action to a neuropeptide Y receptor and is represented by formula (I) [wherein R1 represents hydrogen, cyano, or the like; R represents a group represented by formula (II); X1 represents C1-4 lower alkylene or the like; X2 represents lower alkylene or the like; and Het represents a 5-membered heteroaromatic ring that has at least one nitrogen atom and, in addition, one or two hetero atoms selected from the group consisting of nitrogen, sulfur and oxygen atoms] or to a pharmaceutically acceptable salt thereof.