174291-07-7Relevant articles and documents
Staurosporine and ent-staurosporine: The first total syntheses, prospects for a regioselective approach, and activity profiles
Link,Raghavan, Subharekha,Gallant, Michel,Danishefsky, Samuel J.,Chou,Ballas, Lawrence M.
, p. 2825 - 2842 (2007/10/03)
The total syntheses of staurosporine and ent-staurosporine have been achieved. Both glycosidic bonds were built from glycal precursors. The first was constructed by intermolecular coupling of an indole anion with a 1,2-anhydrosugar derived from an endo-glycal by direct epoxidation. The second bond was assembled from an exo-glycal by intramolecular iodoglycosylation.