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17609-52-8

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17609-52-8 Usage

Chemical Properties

White crystalline powder

Check Digit Verification of cas no

The CAS Registry Mumber 17609-52-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,6,0 and 9 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 17609-52:
(7*1)+(6*7)+(5*6)+(4*0)+(3*9)+(2*5)+(1*2)=118
118 % 10 = 8
So 17609-52-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H15NO4/c18-15(19)11-17(14-9-5-2-6-10-14)16(20)21-12-13-7-3-1-4-8-13/h1-10H,11-12H2,(H,18,19)

17609-52-8 Well-known Company Product Price

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  • TCI America

  • (C2566)  N-Carbobenzoxy-D-2-phenylglycine  >98.0%(HPLC)

  • 17609-52-8

  • 1g

  • 350.00CNY

  • Detail
  • TCI America

  • (C2566)  N-Carbobenzoxy-D-2-phenylglycine  >98.0%(HPLC)

  • 17609-52-8

  • 5g

  • 990.00CNY

  • Detail
  • Aldrich

  • (73113)  Z-D-Phg-OH  ≥99.0% (HPLC)

  • 17609-52-8

  • 73113-5G-F

  • 2,461.68CNY

  • Detail

17609-52-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name {[(Benzyloxy)carbonyl]amino}(phenyl)acetic acid

1.2 Other means of identification

Product number -
Other names N-Carbobenzoxy-D-2-phenylglycine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:17609-52-8 SDS

17609-52-8Relevant articles and documents

Asymmetric recognition of 1-arylethylamines by (R)-phenylglycyl-(R)-phenylglycine and its mechanism

Akazome, Motohiro,Matsuno, Hirozumi,Ogura, Katsuyuki

, p. 2331 - 2336 (1997)

An unprotected dipeptide, (R)-phenylglycyl-(R)-phenylglycine, which is insoluble in water, was shown to be an excellent resolving reagent for racemic 1-arylethylamines. By simply stirring the mixture of the dipeptide and racemic 1-phenylethylamine in presence of water, asymmetric recognition occurred to give a salt of (S)-1-phenylethylamine (95% ee) and the dipeptide. X-Ray crystallographic study of the salt elucidated the crystal structure of the diastereomeric salt, where hydrogen bonding and hydrophobic interaction between the dipeptide and amines play important roles in the construction of layers.

Symmetric benzidine derivatives as anti-HCV agents: Insight into the nature, stereochemistry of the capping amino acid and the size of the terminal capping carbamates

Abadi, Ashraf H.,Abdel Karim, Shereen E.,Abdel-Halim, Mohammad,Ahmed, Nermin S.,Frakolaki, Efseveia,Vassilaki, Niki,Youssef, Youssef H.,Zoidis, Grigoris

, (2020/07/27)

Novel symmetric molecules, bearing a benzidine prolinamide core, two terminal carbamate caps of variable sizes and nature, including natural and unnatural amino acids were developed. Several terminal N-carbamate substituents of the core structure, ranging from linear methyl, ethyl and butyl groups to branching isobutyl group; and an aromatic substituent were also synthesized. Series 1 has hydrophobic AA residues, namely S and R phenylglycine and a terminal carbamate capping group, whereas Series 2 bears sulphur containing amino acids, specifically S and R methionine and the natural R methylcysteine. The novel compounds were tested for their inhibitory activity (EC50) and their cytotoxicity (CC50), using an HCV 1b (Con1) reporter replicon cell line. Compound 4 with the unnatural capping residue, bearing D-Phenylglycine amino acid residue and N-isobutyloxycarbonyl capping group, was the most active within the two series, with EC50 = 0.0067 nM. Moreover, it showed high SI50 > 14788524 and was not cytotoxic at the highest tested concentration (100 μΜ), indicating its safety profile. Compound 4 also inhibited HCV genotypes 2a, 3a and 4a. Compared to the clinically approved NS5A inhibitor Daclatasvir, compound 4 shows higher activity against genotypes 1b and 3a, as well as improved safety profile.

Effective asymmetric Michael addition of anthrone to nitroalkenes using chiral tetraoxacalix[2]arene[2]triazines as organocatalysts

Genc, Hayriye Nevin

, p. 711 - 718 (2019/07/16)

Novel chiral secondary amines bearing a tetraoxacalix[2]arene[2]triazine scaffold were created and used for catalytic asymmetric Michael reaction of anthrone with nitroalkenes. The relevant adducts were obtained in good to excellent yields (82%-98%) and enantioselectivities (75%-98%).

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