17664-93-6

Basic information

• Product Name: H-D-LEU-OBZL P-TOSYLATE
• Synonyms: D-LEUCINE BENZYL ESTER 4-TOLUENESULFONATE SALT;D-LEUCINE BENZYL ESTER P-TOLUENESULFONATE SALT;D-LEUCINE BENZYL ESTER-P-TOSYLATE;D-LEUCINE BENZYL ESTER TOSYLATE;D-LEUCINE-OBZL P-TOSYLATE;H-D-LEU-OBZL P-TOSYLATE;H-D-LEU-OBZL PTSA;H-D-LEU-OBZL TOS
• CAS NO: 17664-93-6
• Molecular Formula: C₇H₈O₃S*C₁₃H₁₉NO₂
• Molecular Weight: 393.5
• Product Categories: Amino Acids;Amino Acid Benzyl Esters;Amino Acids (C-Protected);Biochemistry
• Mol File: 17664-93-6.mol

Chemical Properties

• Melting Point: 158 °C
• Appearance: /
• Refractive Index: -5 ° (C=2, DMF)
• Storage Temp.: Store at RT.
• Solubility: soluble in Methanol
• CAS DataBase Reference: H-D-LEU-OBZL P-TOSYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: H-D-LEU-OBZL P-TOSYLATE(17664-93-6)
• EPA Substance Registry System: H-D-LEU-OBZL P-TOSYLATE(17664-93-6)

Safety Data

• Hazardous Substances Data: 17664-93-6(Hazardous Substances Data)

Usage

Chemical Properties

White powder

InChI:InChI=1/C13H19NO2.C7H8O3S/c1-10(2)8-12(14)13(15)16-9-11-6-4-3-5-7-11;1-6-2-4-7(5-3-6)11(8,9)10/h3-7,10,12H,8-9,14H2,1-2H3;2-5H,1H3,(H,8,9,10)/t12-;/m1./s1

Downstream Products

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• 62058-27-9 Z-(2S,3R)-AHPA-(R)-Leu-OBzl 
• 62058-31-5 (R)-2-((2R,3R)-3-Benzyloxycarbonylamino-2-hydroxy-4-phenyl-butyrylamino)-4-methyl-pentanoic acid benzyl ester 
• 62058-29-1 Z-(2S,3S)-AHPA-(R)-Leu-OBzl 
• 184034-25-1 Hmp-(R)-Leu-OBn 
• 223270-78-8 2-(3-tert-butoxycarbonylamino-propionylamino)-4-methyl-pentanoic acid benzyl ester 
• 223270-79-9 2-[3-(tert-butoxycarbonyl-methyl-amino)-propionylamino]-4-methyl-pentanoic acid benzyl ester 
• 387823-63-4 N-[2-allyl-N-(tert-butoxycarbonyl)-L-prolyl]-D-leucine benzyl ester 
• 282725-28-4 (R)-2-{[(Dimethoxy-phosphoryl)-phenyl-methyl]-amino}-4-methyl-pentanoic acid benzyl ester 
• 223270-90-4 (S)-2-[(R)-2-(3-Amino-propionylamino)-4-methyl-pentanoylamino]-4-methyl-pentanoic acid (S)-1-[((S)-1-carboxy-2-phenyl-ethyl)-methyl-carbamoyl]-3-methyl-butyl ester 
• 223270-91-5 (S)-4-Methyl-2-[(R)-4-methyl-2-(3-methylamino-propionylamino)-pentanoylamino]-pentanoic acid (S)-1-[((S)-1-carboxy-2-phenyl-ethyl)-methyl-carbamoyl]-3-methyl-butyl ester 

Relevant articles and documents

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Compounds of the formula STR1 and pharmaceutically acceptable non-toxic acid addition salts thereof, in which L and D, when applicable, define the chirality; R1 is hydrogen, C1 -C3 primary alkyl, or allyl; R2 is hydrogen or C1 -C3 primary alkyl, subject to the limitation that when R1 is allyl, R2 is hydrogen; R3 is hydrogen or C1 -C3 primary alkyl; R4 is C1 -C4 primary or secondary alkyl; R5 is hydrogen or C1 -C4 primary or secondary alkyl; R6 is hydrogen or C1 -C3 primary alkyl; R7 is hydrogen or C1 -C3 primary alkyl; Y is hydrogen or acetyl; Z is hydrogen of STR2 in which R8 is C1 -C3 alkyl or hydrogen; and W is isopropyl, --VR9, or --CH2 --X--CH3, in which V is O or S, R9 is C1 -C4 alkyl or aralkyl, and X is O, S, or --CH2 --, subject to the limitation that, when W is isopropyl, R7 is C1 -C3 primary alkyl; are useful analgesic agents.