177-15-1

Basic information

• Product Name: Spiro[1,3-oxathiolane-2,1'-cyclohexane]
• Synonyms: 1-Oxa-4-thiaspiro[4.5]decane;Cyclohexanone O,S-ethylenethioacetal;Spiro[1,3-oxathiolane-2,1'-cyclohexane]
• CAS NO: 177-15-1
• Molecular Formula: C₈H₁₄OS
• Molecular Weight: 0
• Mol File: 177-15-1.mol
• Article Data: 37

Chemical Properties

• Boiling Point: 261.6°C at 760 mmHg
• Flash Point: 112°C
• Appearance: /
• Density: 1.09g/cm³
• Vapor Pressure: 0.0186mmHg at 25°C
• Refractive Index: 1.533
• CAS DataBase Reference: Spiro[1,3-oxathiolane-2,1'-cyclohexane](CAS DataBase Reference)
• NIST Chemistry Reference: Spiro[1,3-oxathiolane-2,1'-cyclohexane](177-15-1)
• EPA Substance Registry System: Spiro[1,3-oxathiolane-2,1'-cyclohexane](177-15-1)

Safety Data

• Hazardous Substances Data: 177-15-1(Hazardous Substances Data)

Usage

General Description

Spiro[1,3-oxathiolane-2,1'-cyclohexane] is a chemical compound with a unique spirocyclic structure, containing a six-membered cyclohexane ring fused to a five-membered oxathiolane ring. Spiro[1,3-oxathiolane-2,1'-cyclohexane] is used in the synthesis of pharmaceuticals and agrochemical products, as well as in organic chemistry research. It is also used as a reagent in the formation of various heterocyclic compounds and as a building block in the production of more complex organic molecules. Spiro[1,3-oxathiolane-2,1'-cyclohexane] exhibits interesting chemical and physical properties due to its spirocyclic structure, making it a valuable and versatile compound in the field of organic synthesis.

InChI:InChI=1/C8H14OS/c1-2-4-8(5-3-1)9-6-7-10-8/h1-7H2

Upstream product

• 108-93-0 cyclohexanol 
• 108-94-1 cyclohexanone 
• 177-10-6 1,3-dioxolane-2-spirocyclohexane 
• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 
• 60-24-2 2-hydroxyethanethiol 
• 65225-58-3 2-ethoxy-1,3-oxathiolane 
• 104-15-4 toluene-4-sulfonic acid 
• 71-43-2 benzene 

Downstream Products

• 3778-81-2 2-(cyclohexylthio)ethanol 
• 1666-13-3 diphenyl diselenide 
• 50984-16-2 rac-2-(phenylseleno)cyclohexanone 
• 108-94-1 cyclohexanone 
• 932-92-3 cyclohexyl ethyl ether 
• 127084-51-9 C₂₀H₄₂OSSn 
• 110-82-7 cyclohexane 
• 108-93-0 cyclohexanol 
• 53787-05-6 1-[(2-chloroethyl)sulfanyl]cyclohexane 
• 33266-05-6 6-oxospiro 
• 37457-08-2 cyclohexane-1,1-diylbis(phenylsulfane) 
• 1569-69-3 Cyclohexanethiol 
• 7133-25-7 cyclohexyl ethyl sulfide 
• 10160-79-9 2-cyclohexyloxy-ethanethiol 

Relevant articles and documents

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Ytterbium(III) triflate-catalyzed conversion of carbonyl compounds into 1,3-oxathiolanes in ionic liquids

The reaction of carbonyl compounds with 2-mercapto-ethanol to prepare 1,3-oxathiolanes has been successfully carried out in ionic liquids using ytterbium(III) triflate as a catalyst. Yields of the products are high and the catalyst can be easily recovered

Facile protection of carbonyl compounds as oxathiolanes and thioacetals promoted by PEG1000-based dicationic acidic ionic liquid as chemoselective and recyclable catalyst

Efficient oxathioacetalization and thioacetalization of carbonyl compounds have been achieved in high yields employing PEG1000-based dicationic acidic ionic liquid as a catalyst. The PEG ionic liquid and toluene have the advantages of both homo

Ceric ammonium nitrate as a convenient catalyst for protection of carbonyl compounds as 1,3-oxathianes

A mild and efficient method for the protection of carbonyl compounds as 1,3-oxathianes has been established by the catalytic use of ceric ammonium nitrate at ambient temperature. While different types of aryl and alkyl ketones and aldehydes were protected

Blue LED-Promoted Oxathiacetalization of Aldehydes and Ketones

In synthetic chemistry, the protection of aldehydes and ketones is crucial during multistep synthesis of complex molecules. Organic chemists have paid substantial attention to the synthesis of 1,3-oxathiolanes and 1,3-oxathianes because of their considera

An efficient method for the oxathioacetalization of carbonyl compounds using N-bromosaccharin as a catalyst

A mild and highly chemoselective method for the preparation of oxathiolane from aliphatic and aromatic aldehydes and ketones with 2-mercaptoethanol in the presence of catalytic amount of N-bromosaccharin at room temperature is reported.