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(3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid monohydrochloride is a complex organic compound with a unique molecular structure that features a fluoroquinolone core. (3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid monohydrochloride is characterized by the presence of a fluorine atom at the 9-position, a methyl group at the 3-position, and a 4-methyl-1-piperazinyl substituent at the 10-position. The molecule also contains a 7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine ring system and a carboxylic acid group at the 6-position, which is protonated to form a monohydrochloride salt. This intricate arrangement of functional groups endows the compound with potential biological activities and applications in various fields.

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  • (3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid monohydrochloride

    Cas No: 177325-13-2

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  • (3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid monohydrochloride

    Cas No: 177325-13-2

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  • 177325-13-2 Structure
  • Basic information

    1. Product Name: (3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid monohydrochloride
    2. Synonyms: LEVOFLOXACIN HYDROCHLORIDE;(3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid monohydrochloride;7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacid, 9-fluoro-2,3-dihydro-3-Methyl-10-(4-Methyl-1-piperazinyl)-7-oxo-,hydrochloride (1:1), (3S)-;3S)-9-Fluoro-2,3-dihydro-3-Methyl-10-(4-Methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid Monohydrochlori;(S)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride;-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride;-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl);usp27 99% Levofloxacin white powder Antibacterial
    3. CAS NO:177325-13-2
    4. Molecular Formula: C18H20FN3O4.HCl
    5. Molecular Weight: 397.83
    6. EINECS: 1312995-182-4
    7. Product Categories: Pharmaceutical raw materials
    8. Mol File: 177325-13-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 571.5 °C at 760 mmHg
    3. Flash Point: 299.4 °C
    4. Appearance: /
    5. Density: N/A
    6. Vapor Pressure: 6.7E-14mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    9. Solubility: Aqueous Base (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
    10. CAS DataBase Reference: (3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid monohydrochloride(CAS DataBase Reference)
    11. NIST Chemistry Reference: (3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid monohydrochloride(177325-13-2)
    12. EPA Substance Registry System: (3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid monohydrochloride(177325-13-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 177325-13-2(Hazardous Substances Data)

177325-13-2 Usage

Uses

Used in Pharmaceutical Industry:
(3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid monohydrochloride is used as a broad-spectrum antibiotic for the treatment of various bacterial infections. As a fluoroquinolone, it functions as an inhibitor of two essential bacterial enzymes, DNA gyrase and topoisomerase IV, which are involved in DNA replication, transcription, and repair. By inhibiting these enzymes, the compound disrupts the bacterial DNA synthesis, ultimately leading to the death of the bacteria and clearing the infection.
Used in Research and Development:
In addition to its clinical applications, (3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid monohydrochloride serves as a valuable compound for research and development in the field of medicinal chemistry. Its unique structure and biological activity make it an attractive candidate for further investigation into its mechanism of action, potential synergistic effects with other drugs, and the development of new derivatives with improved properties and therapeutic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 177325-13-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,7,3,2 and 5 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 177325-13:
(8*1)+(7*7)+(6*7)+(5*3)+(4*2)+(3*5)+(2*1)+(1*3)=142
142 % 10 = 2
So 177325-13-2 is a valid CAS Registry Number.
InChI:InChI=1/C18H20FN3O4.ClH/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21;/h7-8,10H,3-6,9H2,1-2H3,(H,24,25);1H/t10-;/m0./s1

177325-13-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name Levofloxacin hydrochloride

1.2 Other means of identification

Product number -
Other names S454

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:177325-13-2 SDS

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