1776-87-0

Basic information

• Product Name: Phosphonic acid, [hydroxy(4-nitrophenyl)methyl]-, diethyl ester
• Synonyms: diethyl [hydroxy(4-nitrophenyl)methyl]phosphonate;diethyl (hydroxy)(4-nitrophenyl)methylphosphonate;diethyl α-hydroxy-4-nitrobenzylphosphonate;(α-hydroxy-4-nitro-benzyl)-phosphonic acid diethyl ester;[hydroxy-(4-nitro-phenyl)-methyl]-phosphonic acid diethyl ester;diethyl hydroxy(4-nitrophenyl)methylphosphonate
• CAS NO: 1776-87-0
• Molecular Formula: C11H16NO6P
• Molecular Weight: 289.225
• Mol File: 1776-87-0.mol
• Article Data: 49

Chemical Properties

• Melting Point: 85 °C (ethanol)
• CAS DataBase Reference: Phosphonic acid, [hydroxy(4-nitrophenyl)methyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [hydroxy(4-nitrophenyl)methyl]-, diethyl ester(1776-87-0)
• EPA Substance Registry System: Phosphonic acid, [hydroxy(4-nitrophenyl)methyl]-, diethyl ester(1776-87-0)

Safety Data

• Hazardous Substances Data: 1776-87-0(Hazardous Substances Data)

Usage

General Description

Phosphonic acid, [hydroxy(4-nitrophenyl)methyl]-, diethyl ester is a chemical compound with the formula C11H15NO7P. It is commonly used in the production of agricultural chemicals, as well as in industrial and pharmaceutical applications. Phosphonic acid, [hydroxy(4-nitrophenyl)methyl]-, diethyl ester is an ester of phosphonic acid and is characterized by the presence of a hydroxy group and a 4-nitrophenylmethyl group. It is used as a chelating agent and a corrosion inhibitor in various industrial processes. Additionally, it has been studied for its potential use as an anti-tumor agent and in the treatment of neurodegenerative diseases. However, it is important to handle this compound with care, as it can be hazardous if not properly managed.

Upstream product

• 762-04-9 Diethyl phosphonate 
• 555-16-8 4-nitrobenzaldehdye 
• 13716-45-5 diethyl trimethylsilyl phosphite 
• 122-52-1 triethyl phosphite 
• 762-04-9 phosphonic acid diethyl ester 

Downstream Products

• 1606168-75-5 (4-{[6-(3-aminophenyl)pyrimidin-4-yl]amino}benzyl)phosphonic acid 
• 1606168-73-3 (4-{[6-(3-nitrophenyl)pyrimidin-4-yl]amino}benzyl)phosphonic acid 
• 1606168-69-7 diethyl (4-{[6-(3-aminophenyl)pyrimidin-4-yl]amino}benzyl)phosphonate 
• 1606168-67-5 diethyl [hydroxy(4-{[6-(3-nitrophenyl)pyrimidin-4-yl]amino}phenyl)methyl]phosphonate 
• 1606168-65-3 diethyl (4-{[6-(3-nitrophenyl)pyrimidin-4-yl]amino}benzyl)phosphonate 
• 1606168-63-1 diethyl [hydroxy(4-{[6-(2-methoxyphenyl)pyrimidin-4-yl]amino}phenyl)methyl]phosphonate 
• 1606168-61-9 diethyl (4-{[6-(2-methoxyphenyl)pyrimidin-4-yl]amino}benzyl)phosphonate 
• 20074-79-7 diethyl (4-aminobenzyl)phosphonate 
• 1333318-24-3 C₆H₁₃N*C₁₄H₂₂NO₅P 
• 1333318-22-1 C₆H₁₃N*C₁₇H₂₇FNO₄P 
• 1333318-21-0 C₆H₁₃N*C₁₇H₂₈NO₅P 
• 1333318-19-6 C₆H₁₃N*C₂₁H₃₅BrNO₄P 
• 1351930-94-3 C₂₁H₃₅BrNO₄P 
• 1333318-16-3 C₂₅H₄₃BrNO₄P 

Relevant articles and documents

Method for synthesizing aromatic ring-containing alpha-hydroxyphosphonate through copper catalysis

The invention relates to a method for synthesizing aromatic ring-containing alpha-hydroxyphosphonate through copper catalysis. The method comprises the following steps: dissolving diethyl phosphite and aromatic aldehyde in an organic solvent, adding a cop

Rational synthesis of α-hydroxyphosphonic derivatives including dronic acids

New, green methods have been elaborated for the syntheses of α-hydroxyphosphonates and α-hydroxymethylenebisphosphonic derivatives (HMBPs, dronates). α-Hydroxyphosphonates were prepared via the Pudovik reaction, while the synthesis of HMBPs has been performed in the three-component reaction of carboxylic acids, phosphorus trichloride and phosphorus acid.

Hydrophosphonylation of aldehydes catalyzed by cyclopentadienyl ruthenium(II) complexes

This work reports the first method for the synthesis of α-hydroxyphosphonates from aldehydes catalyzed by cyclopentadienyl ruthenium(II) complexes. The best results were obtained using the system HP(O)(OEt)2/[RuClCp(PPh3)2