177948-70-8

Basic information

• Product Name: (R)-3-BENZYLOXY-PYRROLIDINE
• Synonyms: pyrrolidine, 3-(phenylmethoxy)-, (3R)-
• CAS NO: 177948-70-8
• Molecular Formula: C₁₁H₁₅NO
• Molecular Weight: 177.24
• Mol File: 177948-70-8.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 269.2°C at 760 mmHg
• Flash Point: 106.7°C
• Appearance: /
• Density: 1.05g/cm³
• Vapor Pressure: 0.00737mmHg at 25°C
• Refractive Index: 1.545
• CAS DataBase Reference: (R)-3-BENZYLOXY-PYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-BENZYLOXY-PYRROLIDINE(177948-70-8)
• EPA Substance Registry System: (R)-3-BENZYLOXY-PYRROLIDINE(177948-70-8)

Safety Data

• Hazardous Substances Data: 177948-70-8(Hazardous Substances Data)

Usage

General Description

(R)-3-Benzyloxy-pyrrolidine is a chemical compound with the molecular formula C12H17NO and a molecular weight of 191.27 g/mol. It is a pyrrolidine derivative that contains a benzyl ether group attached to the nitrogen atom. (R)-3-BENZYLOXY-PYRROLIDINE is commonly used as a chiral building block in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It is known for its ability to act as a versatile intermediate in organic synthesis due to its stereochemical properties and functional groups. The (R)-3-Benzyloxy-pyrrolidine compound is also used in the development of chiral catalysts and ligands for asymmetric synthesis. It is important in the production of various biologically active molecules and can be employed in the preparation of numerous heterocyclic compounds.

InChI:InChI=1/C11H15NO/c1-2-4-10(5-3-1)9-13-11-6-7-12-8-11/h1-5,11-12H,6-9H2/t11-/m1/s1

Upstream product

• 100-39-0 benzyl bromide 
• 40499-83-0 (3R)-pyrrolidinol 
• 927819-90-7 (R)-3-(benzyloxy)pyrrolidine hydrochloride 
• 196862-46-1 (R)-3-(benzyloxy)-4-chloro-butanenitrile 
• 177947-67-0 (3R)-N-(tert-butyloxycarbonyl)-3-(benzyloxy)pyrrolidine 

Downstream Products

• 927819-92-9 (R)-3-benzyloxypyrrolidine p-toluenesulfonate 
• 927819-95-2 3(R)-benzyloxypyrrolidine (L)-tartrate 
• 927819-96-3 3(R)-benzyloxypyrrolidine (D)-tartrate 
• 927819-97-4 3(R)-benzyloxypyrrolidine (L)-aspartate 
• 927819-94-1 (R)-3-benzyloxypyrrolidine benzoate 
• 927819-98-5 3(R)-benzyloxypyrrolidine (D)-aspartate 
• 927819-91-8 (R)-3-benzyloxypyrrolidine hydrobromide 
• 927819-93-0 (R)-3-benzyloxypyrrolidine sulfate 
• 900513-88-4 (1R,2R)-2-[(R)-3-(benzyloxy)pyrrolidin-1-yl]cyclohexanol 
• 1370354-77-0 C₂₇H₃₇NO₅ 
• 1370354-64-5 C₂₇H₃₇NO₅ 
• 927819-90-7 (R)-3-(benzyloxy)pyrrolidine hydrochloride 
• 40499-83-0 (3R)-pyrrolidinol 

Relevant articles and documents

A Recyclable Chiral 2-(Triphenylmethyl)pyrrolidine Organocatalyst Anchored to [60]Fullerene

Hybridization of a chiral 3-hydroxy-2-trityl-pyrrolidine deriving from (R)-pyrrolidinol with [60]fullerene via click chemistry provides a highly efficient supported enantioselective organocatalyst, which was successfully exploited in a Michael addition of

NOVEL BETULINIC SUBSTITUTED AMIDE DERIVATIVES AS HIV INHIBITORS

The present invention relates to novel betulinic substituted amide compounds of formula (I); and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, X, Y, Z1, Z2, Z3 and are Formula (II) as defined herein. The invention novel betulinic substituted amide derivatives, related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases.

PROCESS FOR PRODUCTION OF BENZYLOXYPYRROLIDINE DERIVATIVE, AND PROCESS FOR PRODUCTION OF HYDROCHLORIDE SALT POWDER OF OPTICALLY ACTIVE BENZYLOXYPYRROLIDINE DERIVATIVE

Provided are: a process for production of a benzyloxypyrrolidine derivative in high yield and safety, and a process for production of a hydrochloride powder of a benzyloxypyrrolidine derivative in high yield and safety; the process for production of a benzyloxypyrrolidine derivative expressed by the general formula (2) [Chemical formula 2], in reacting a pyrrolidinol derivative represented by the general formula (1) [Chemical formula 1 with a benzyl halide derivative in the presence of an alkali metal hydroxide, wherein the reaction is carried out in either of the following conditions A or B; condition A: an aprotic polar solvent, and condition B: an aliphatic ether solvent containing a phase transfer catalyst: