179524-33-5Relevant articles and documents
Aromatic heterocyclic derivatives as enzyme inhibitors
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Page column 88-89, (2010/02/04)
The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.
Heteroaryl protease inhibitors and diagnostic imaging agents
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, (2008/06/13)
Ketothiazole alkoxyguanidine and aminoguanidine analogs are described, including compounds of the Formula I: wherein X is O or NR9and Het, A, R1, R7, R8, R12, R13, Ra, Rb/s
ANTITHROMBOTIC AGENTS
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, (2008/06/13)
Compounds of formula (I): Are antithrombotic agents, having utility in a variety of therapeutic areas including the prevention and/or treatment of deep vein thrombosis (DVT) after surgery, major medical illness, paralysis, malignancy, prolonged immobilisa