180608-81-5Relevant articles and documents
Synthesis of α-substituted and α,α-disubstituted α-amino acids by controlled mono- and dialkylation of ethyl N-diphenylmethyleneglycinate
Ezquerra,Pedregal,Moreno-Manas,Pleixats,Roglans
, p. 8535 - 8538 (1993)
Ethyl N-diphenylmethyleneglycinate reacts with one equivalent of alkylating agents in the presence of powdered potassium carbonate to afford, after hydrolysis, monoalkylated glycine esters. A similar process using two equivalents of alkylating agents in t