181028-67-1Relevant articles and documents
Design and synthesis of an α-mannosyl terpenoid as selective inhibitor of P-selectin
Ikeda, Tsuyoshi,Kajimoto, Tetsuya,Kondo, Hirosato,Wong, Chi-Huey
, p. 2485 - 2490 (1997)
In an effort to develop the structural and functional mimics of the tetrasaccharide sialyl Lewis x as selective inhibitors of P-selectin, we have designed a mannosyl terpenoid derivative that selectively inhibits P-selectin within an IC50 value of 60 μM, but exhibits no inhibition activity against E- and L-selectins.