18189-42-9

Basic information

• Product Name: 3-(ETHOXYCARBONYL)BENZOIC ACID
• Synonyms: 3-(ETHOXYCARBONYL)BENZOIC ACID;RARECHEM AX BL 0022;1,3-Benzenedicarboxylic acid, Monoethyl ester
• CAS NO: 18189-42-9
• Molecular Formula: C₁₀H₁₀O₄
• Molecular Weight: 194.18
• Mol File: 18189-42-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 115-117 °C(Solv: water (7732-18-5))
• Boiling Point: 349.0±25.0 °C(Predicted)
• Appearance: /
• Density: 1.241±0.06 g/cm3(Predicted)
• PKA: 3.83±0.10(Predicted)
• CAS DataBase Reference: 3-(ETHOXYCARBONYL)BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(ETHOXYCARBONYL)BENZOIC ACID(18189-42-9)
• EPA Substance Registry System: 3-(ETHOXYCARBONYL)BENZOIC ACID(18189-42-9)

Safety Data

• Hazardous Substances Data: 18189-42-9(Hazardous Substances Data)

Upstream product

• 636-53-3 diethyl isophthalate 
• 201230-82-2 carbon monoxide 
• 58313-23-8 3-iodobenzoic acid methyl ester 
• 64-17-5 ethanol 
• 99-63-8 benzene-1,3-dicarbonyl dichloride 
• 121-91-5 isophthalic acid 
• 67326-20-9 3-carbethoxybenzoyl chloride 
• 124-38-9 carbon dioxide 
• 15226-74-1 dicobalt octacarbonyl 
• 585-76-2 m-bromobenzoic acid 

Downstream Products

• 862014-10-6 N-prop-2-ynyl-isophthalamic acid ethyl ester 
• 1247691-89-9 C₁₅H₂₀N₂O₅ 
• 757965-28-9 isophthalic acid mono(N-butylamide) 
• 823195-12-6 3-(3-thiophen-2-yl-[1,2,4]oxadiazol-5-yl)-benzoic acid ethyl ester 
• 67326-20-9 3-carbethoxybenzoyl chloride 

Relevant articles and documents

One-pot synthetic method for m-acetylbenzoic acid

The invention relates to a synthetic method, in particular to a one-pot synthetic method for m-acetylbenzoic acid. According to the one-pot synthetic method for the m-acetylbenzoic acid, there is no need to purify an intermediate product. The reaction equation of the m-acetylbenzoic acid is shown in the description, wherein R refers to methyl or ethyl, and R1 refers to methyl or ethyl or n-propyl. Compared with synthetic methods in the prior art, the synthetic method has the advantages that raw materials are low in price and easy to get, reaction conditions are mild, the obtained intermediate product can be directly used for a reaction in a next step without being separated and purified, and therefore process cost is greatly lowered.

Cobalt carbonyl as an effective CO source in one-pot synthesis of esters from aryl halides

For the first time, we have successfully applied Co2(CO) 8 as an effective carbonyl source for the Pd catalysed alkoxycarbonylation of aryl halides affording the corresponding aryl esters under mild microwave conditions. A wide variety of esters and carbonyl derivatives were prepared using this protocol.

Green Catalysis: Hydroxycarbonylation of Aryl Halides in Water Catalyzed by an Amphiphilic Resin-Supported Phosphine-Palladium Complex

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