184289-85-8 Usage
General Description
Benzyl spiro[indole-3,4'-piperidine]-1'-carboxylate is a synthetic chemical compound with a complex molecular structure. It belongs to the spiro compound family, which are characterized by a unique arrangement of atoms. This particular compound consists of a benzyl group, a spiro[indole-3,4'-piperidine] core, and a carboxylate functional group. It is commonly used in organic chemistry research and pharmaceutical development, where it may serve as a building block for creating new drugs or as a reference compound for testing the biological activity of similar molecules. The specific properties and potential applications of benzyl spiro[indole-3,4'-piperidine]-1'-carboxylate may vary depending on its context and the specific chemical reactions it undergoes.
Check Digit Verification of cas no
The CAS Registry Mumber 184289-85-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,4,2,8 and 9 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 184289-85:
(8*1)+(7*8)+(6*4)+(5*2)+(4*8)+(3*9)+(2*8)+(1*5)=178
178 % 10 = 8
So 184289-85-8 is a valid CAS Registry Number.
184289-85-8Relevant articles and documents
Ugi-type reactions of spirocyclic indolenines as a platform for compound library generation
Estévez, Verónica,Kloeters, Laura,Kwietniewska, Natalia,Vicente-García, Esther,Ruijter, Eelco,Orru, Romano V.A.
, p. 376 - 380 (2017/02/10)
A simple and efficient method for the synthesis of highly substituted spiroindoline derivatives is presented. A Fischer indolization is combined with Ugi-type reactions to explore the chemical space concerning this privileged structure. Moreover, spiropip
Synthesis of the orally active spiroindoline-based Growth Hormone Secretagogue, MK-677
Maligres, Peter E.,Houpis, Ioannis,Rossen, Kai,Molina, Audrey,Sager, Jess,Upadhyay, Veena,Wells, Kenneth M.,Reamer, Robert A.,Lynch, Joseph E.,Askin, David,Volante,Reider, Paul J.,Houghton, Peter
, p. 10983 - 10992 (2007/10/03)
The preparation of the Merck Growth Hormone Secretagogue; MK-677 is described. A Fischer indole/reduction based strategy provides the novel spiroindoline nucleus of this potent compound. This optimized sequence necessitates the isolation of only one intermediate 10 and provides MK-677 in 48% overall yield from isonipecotic acid 3.
