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CM-272 is a chemical compound that functions as a selective inhibitor of the proto-oncogene c-Met, a key player in the development and progression of cancer. It is recognized for its ability to effectively inhibit the growth of various tumor cell lines, particularly those from lung, breast, and prostate cancers. By binding to the c-Met protein and blocking its activity, CM-272 leads to a reduction in the proliferation and survival of cancer cells, positioning it as a promising candidate for the treatment of c-Met-dependent cancers and further development in cancer therapy.

1846570-31-7

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1846570-31-7 Usage

Uses

Used in Pharmaceutical Industry:
CM-272 is used as a therapeutic agent for targeting c-Met-dependent cancers due to its ability to inhibit the growth of tumor cells and its potential to enhance the efficacy of conventional cancer treatments.
Used in Cancer Research:
CM-272 is used as a research tool for studying the role of the c-Met protein in cancer development and progression, providing insights into the mechanisms of action and potential therapeutic strategies against c-Met-driven malignancies.
Used in Drug Development:
CM-272 is utilized in the development of novel cancer therapies, with its selective inhibition of c-Met offering a targeted approach to treating cancers that rely on this protein for growth and survival.
Used in Preclinical Studies:
CM-272 is employed in preclinical studies to evaluate its safety, efficacy, and potential synergistic effects when combined with other cancer treatments, contributing to the advancement of cancer therapeutics.

Check Digit Verification of cas no

The CAS Registry Mumber 1846570-31-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,4,6,5,7 and 0 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1846570-31:
(9*1)+(8*8)+(7*4)+(6*6)+(5*5)+(4*7)+(3*0)+(2*3)+(1*1)=197
197 % 10 = 7
So 1846570-31-7 is a valid CAS Registry Number.

1846570-31-7Downstream Products

1846570-31-7Relevant academic research and scientific papers

Discovery of AL-GDa62 as a Potential Synthetic Lethal Lead for the Treatment of Gastric Cancer

Beetham, Henry,Bougen-Zhukov, Nicola,Cameron, Scott A.,Evans, Gary B.,Fraser, Michael G.,Guilford, Parry J.,Harris, Lawrence D.,Luxenburger, Andreas,Schmidt, Dorian

, p. 18114 - 18142 (2021/12/17)

Diffuse gastric cancer and lobular breast cancer are aggressive malignancies that are frequently associated with inactivating mutations in the tumor suppressor gene CDH1. Synthetic lethal (SL) vulnerabilities arising from CDH1 dysfunction represent attrac

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