1863-39-4 Usage
General Description
3-beta,17-alpha-dihydroxypregn-5-en-20-one 3-acetate, also known as 17-alpha-hydroxyprogesterone acetate, is a synthetic progestin derived from 17-alpha-hydroxyprogesterone. It is commonly used in hormonal contraceptives and hormone replacement therapy due to its ability to mimic the effects of the natural hormone progesterone. This chemical acts on the lining of the uterus, preventing the release of the egg during the menstrual cycle and making it difficult for sperm to reach the egg, thus preventing pregnancy. Additionally, it can also be used to regulate irregular menstrual cycles and treat symptoms of menopause. The acetate group attached to the hormone enhances its stability and solubility, making it more suitable for pharmaceutical use.
Check Digit Verification of cas no
The CAS Registry Mumber 1863-39-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,6 and 3 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1863-39:
(6*1)+(5*8)+(4*6)+(3*3)+(2*3)+(1*9)=94
94 % 10 = 4
So 1863-39-4 is a valid CAS Registry Number.
InChI:InChI=1/C23H34O4/c1-14(24)23(26)12-9-20-18-6-5-16-13-17(27-15(2)25)7-10-21(16,3)19(18)8-11-22(20,23)4/h5,17-20,26H,6-13H2,1-4H3
1863-39-4Relevant articles and documents
SYNTHESIS OF PREGNANE DERIVATIVES
Popova, E. V.,Andryushina, V. A.,Grinenko, G. S.
, p. 302 - 304 (1984)
Pregnane derivatives have been obtained from the cyanohydrins of androst-4-en-3,17-dione and of 3β-acetoxyandrost-5-en-17-one.It has been shown that when both a nitrile group and an ethylenedioxy group are present in a androstane derivative a Grignard reaction in anisole takes place simultaneously at the two groups.
Further syntheses of cyproterone acetate
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Page/Page column 16; 27; 29; 31, (2010/02/07)
The present invention relates to improved methods for synthesising cyproterone acetate (17α-Acetoxy-6-chloro-1α, 2α-methylene-4,6-pregnadiene-3,20-dione) from solasodine. The methods of the invention are shorter as those of the prior art and therefore more economic.
Steroid derivatives. LXXVI. Simplified preparation of cortexolone (cortodoxone)
Schwarz,Protiva,Mickova,Bockova
, p. 231 - 233 (2007/10/10)
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