187164-20-1

Basic information

• Product Name: (S)-2-bromo-1-(2,4-dichlorophenyl)ethanol
• CAS NO: 187164-20-1
• Molecular Weight: 269.953
• Mol File: 187164-20-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (S)-2-bromo-1-(2,4-dichlorophenyl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-bromo-1-(2,4-dichlorophenyl)ethanol(187164-20-1)
• EPA Substance Registry System: (S)-2-bromo-1-(2,4-dichlorophenyl)ethanol(187164-20-1)

Safety Data

• Hazardous Substances Data: 187164-20-1(Hazardous Substances Data)

Usage

General Description

(S)-2-bromo-1-(2,4-dichlorophenyl)ethanol is a chemical compound that belongs to the class of organic compounds known as phenylpropanoids. It is a chiral molecule, with a specific arrangement of atoms around its central carbon atom. (S)-2-bromo-1-(2,4-dichlorophenyl)ethanol is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Its bromine and chlorine atoms make it useful for diverse chemical reactions, and it is often employed as a reagent in organic synthesis. Additionally, this compound has shown potential as an antimicrobial agent, and its ability to inhibit the growth of bacteria and other microorganisms makes it useful in the development of antibacterial products. Overall, (S)-2-bromo-1-(2,4-dichlorophenyl)ethanol is a versatile and important compound with a wide range of applications in various industries.

Upstream product

• 2631-72-3 2,4-dichlorophenacyl bromide 
• 112022-81-8 (S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole 

Downstream Products

• 187164-19-8 luliconazole 
• 187164-19-8 [(4R)-4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-(1H-imidazol-1-yl)acetonitrile 
• 27646-28-2 (S)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethan-1-ol 
• 141394-11-8 (S)-2-(2,4-dichlorophenyl)oxirane 

Relevant articles and documents

COMPOUNDS OF R-(-)-(E)-[4-(2,4-DICHLOROPHENYL)-1,3-DITHIOLAN-2-YLIDENE]-1 -IMIDAZOLYLACETONITRILE-HA (LULICONAZOLE-HA) AS ANTIFUNGALS

The present invention refers to compound R-(-)-(E)-[4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-1-imidazolylacetonitrile HA, wherein HA is an acid; and to a process for their preparation. The present invention also refers to the use of compound R-(-)-(E)-[4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-1-imidazolylacetonitrile HA for the manufacturing of luliconazole and pharmaceutically acceptable salts or co-crystals thereof in high yield and purity. The present invention further is directed to this compound R-(-)-(E)-[4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-1-imidazolylacetonitrile HA in the treatment of fungal infections.

A switch in enantiomer preference between mitochondrial F1F 0-ATPase chemotypes

The preferred absolute configuration of two series of F1F 0-ATP synthase inhibitors was determined. Although the configuration of the active enantiomer in each series is different, each series presents the same 'triaryl' pharmacophor