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18927-05-4

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18927-05-4 Usage

Uses

Methyl 3-methoxyphenylacetate is an important organic intermediate. It can be used in agrochemical, pharmaceutical and dyestuff field.

Check Digit Verification of cas no

The CAS Registry Mumber 18927-05-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,9,2 and 7 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 18927-05:
(7*1)+(6*8)+(5*9)+(4*2)+(3*7)+(2*0)+(1*5)=134
134 % 10 = 4
So 18927-05-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H12O3/c1-12-9-5-3-4-8(6-9)7-10(11)13-2/h3-6H,7H2,1-2H3

18927-05-4 Well-known Company Product Price

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  • Alfa Aesar

  • (B20237)  Methyl 3-methoxyphenylacetate, 97%   

  • 18927-05-4

  • 2.5g

  • 600.0CNY

  • Detail
  • Alfa Aesar

  • (B20237)  Methyl 3-methoxyphenylacetate, 97%   

  • 18927-05-4

  • 10g

  • 1278.0CNY

  • Detail
  • Alfa Aesar

  • (B20237)  Methyl 3-methoxyphenylacetate, 97%   

  • 18927-05-4

  • 50g

  • 5430.0CNY

  • Detail

18927-05-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 2-(3-methoxyphenyl)acetate

1.2 Other means of identification

Product number -
Other names Methyl 2-(3-methoxyphenyl)acetate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18927-05-4 SDS

18927-05-4Relevant articles and documents

Synthesis, in-vitro, in-vivo anti-inflammatory activities and molecular docking studies of acyl and salicylic acid hydrazide derivatives

Ali, Gowhar,Ashraf, Zaman,Hussain, Izhar,Khushal, Adil,Mumtaz, Amara,Munir, Abida,Rashid, Umer,Sadiq, Abdul,Saeed Jan, Muhammad,Saeed, Kiran,Ullah Mughal, Ehsan,Ullah, Rahim

, (2020)

Over the course of time several drugs have been synthesized and are available in market for the treatment of inflammation. However, they were unable to cure effectively and associated with side effects. To effectively deal with such diseases, heterocycles and their derivatives have gained their special position. For this reason 1,3,4-oxadiazole (15–16), 1,2,4-triazole (17–18), Schiff base (19–24) and 3,5-disubstituted pyrazole (25) derivatives were synthesized starting from salicylic acid and acyl acid hydrazides (12–14) as COX-1 and COX-2 inhibitors. In vivo anti-inflammatory activities were also tested by carrageenan-induced mice paw edema against albino mice of any sex. Structures of all the synthesized compounds were confirmed by FT-IR and 1H NMR analysis. Schiff base derivative of 4-amiontirazole (24) with IC50 value of 1.76 ± 0.05 (COX-2) and 117.8 ± 2.59 emerged as potent COX-2 inhibitor. Furthermore, we also performed in-vivo anti-inflammatory investigations by using carrageenan induced paw edema test. From in-vivo anti-inflammatory activities, it was found that after 1 h the maximum percentage inhibition 15.8% was observed by compound 14 which is comparable with that of the standard drug followed by the compound 18 with percentage inhibition of 10.5%. After 3 h, the maximum percentage inhibition was observed by compound 18 with 22.2% and compound 14 with 16.7%. After 5 h the maximum percentage inhibition was observed by compound 18 with 29.4% followed by compound 16 with 23.5%. We further explore the mechanism of the inhibition by using docking simulations. Docking studies revealed that the selective COX-2 inhibitors established interactions with additional COX-2 enzyme pocket residues.

Magnesiate Addition/Ring-Expansion Strategy to Access the 6-7-6 Tricyclic Core of Hetisine-Type C20-Diterpenoid Alkaloids

Pflueger, Jason J.,Morrill, Louis C.,Degruyter, Justine N.,Perea, Melecio A.,Sarpong, Richmond

, p. 4632 - 4635 (2017)

A synthetic strategy to access the fused 6-7-6 tricyclic core of hetisine-type C20-diterpenoid alkaloids is reported. This strategy employs a Diels-Alder cycloaddition to assemble a fused bicyclic anhydride intermediate, which is elaborated to

Green Esterification of Carboxylic Acids Promoted by tert-Butyl Nitrite

Cheng, Xionglve,Jiang, Gangzhong,Li, Xingxing,Tao, Suyan,Wan, Xiaobing,Zhao, Yanwei,Zheng, Yonggao

supporting information, p. 2713 - 2718 (2021/06/25)

In this work, the green esterification of carboxylic acids promoted by tert-butyl nitrite has been well developed. This transformation is compatible with a broad range of substrates and exhibits excellent functional group tolerance. Various drugs and substituted amino acids are applicable to this reaction under near neutral conditions, with good to excellent yields.

Blue Light-Promoted N?H Insertion of Carbazoles, Pyrazoles and 1,2,3-Triazoles into Aryldiazoacetates

Stivanin, Mateus L.,Fernandes, Alessandra A. G.,da Silva, Amanda F.,Okada, Celso Y.,Jurberg, Igor D.

supporting information, p. 1106 - 1111 (2020/01/25)

Blue light irradiation of aryldiazoacetates leads to the formation of free carbenes, which can react with carbazoles, pyrazoles and 1,2,3-triazoles to afford the corresponding N?H inserted products. These reactions are performed under air and at room temperature, allowing the mild preparation of a variety of motifs found in biologically relevant targets. (Figure presented.).

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