1911-74-6 Usage
General Description
Trityl-L-Proline is a chemical compound that is derived from the amino acid proline. It is commonly used as a protecting group for the carboxylic acid functional group in organic synthesis. The trityl group provides stability and protection to the carboxylic acid, allowing for selective reactions to take place without affecting other parts of the molecule. Trityl-L-Proline is useful in the production of pharmaceuticals, agrochemicals, and other fine chemicals. It is also an important reagent in peptide synthesis, where it is used to protect the carboxyl group of proline during the assembly of peptide chains. Overall, Trityl-L-Proline plays a critical role in the development and production of a wide range of organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 1911-74-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,1 and 1 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1911-74:
(6*1)+(5*9)+(4*1)+(3*1)+(2*7)+(1*4)=76
76 % 10 = 6
So 1911-74-6 is a valid CAS Registry Number.
1911-74-6Relevant articles and documents
TRITYLATION REACTIONS BASED ON METALLIC CATALYSIS
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Page/Page column 22-23, (2010/11/25)
The invention relates to a method for preparing tritylated compounds in which protic functional groups are protected with the triphenylmethyl group, method based on the homogeneous catalysis exercised by salts or metal complexes in organic solvents. The invention relates in particular to a method for the selective tritylation of some groups, obtained both directly and by selective detritylation, with methods based on metallic catalysis. The application to amino acids, typical substrates not suitable to be subjected as such to homogeneous tritylations in organic solvents, indicates the ability of the method to extend also to hydrophilic substrates. The method allows to obtain with high yield pertrityl amino acids, N-tritylamino acids or amino acids tritylated only in lateral chain, compounds which heretofore were either difficult to obtain in aqueous solvents or obtainable through indirect methods. All, in any case, are important intermediates in peptide synthesis.
