1911578-75-0

Basic information

• Product Name: C₂₇H₃₅N₆O₈P
• CAS NO: 1911578-75-0
• Molecular Weight: 602.584
• Mol File: 1911578-75-0.mol
• Article Data: 28

Chemical Properties

• CAS DataBase Reference: C₂₇H₃₅N₆O₈P(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₇H₃₅N₆O₈P(1911578-75-0)
• EPA Substance Registry System: C₂₇H₃₅N₆O₈P(1911578-75-0)

Safety Data

• Hazardous Substances Data: 1911578-75-0(Hazardous Substances Data)

Usage

General Description

C27H35N6O8P is the molecular formula for the chemical compound adenosine triphosphate (ATP). ATP is a critical molecule for energy transfer in cells and is often referred to as the "energy currency" of the cell. It is composed of a nucleoside (adenosine) and three phosphate groups. The release of one phosphate group from ATP releases a large amount of energy that is used to power many cellular processes, such as muscle contractions, nerve impulses, and protein synthesis. ATP is also involved in the storage and transfer of energy within the cell. Overall, ATP plays a crucial role in the energy metabolism of living organisms and is essential for maintaining cellular function and survival.

Upstream product

• 1369903-46-7 (2S,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-carbonitrile 
• 1355049-95-4 (2S,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile 
• 1355049-94-3 (3R,4R,5R)-2-(4-aminopyrrole-[2,1-f][1,2,4]-triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol 
• 770-12-7 O-phenyl phosphorodichloridate 
• 1191237-80-5 (3αR,4R,6R,6αR)-4-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carbonitrile 

Downstream Products

• 1911579-04-8 GS-704277 

Relevant articles and documents

Total synthesis of remdesivir

Remdesivir, the first drug approved by the FDA to treat COVID-19, is in high demand for patients infected with the SARS-CoV-2 virus. Herein, we report a facile approach minimizing the protecting group manipulations to afford remdesivir in good overall yield.

ISOMORPHS OF REMDESIVIR AND METHODS FOR SYNTHESIS OF SAME

A new isoform of 2-ethylbutyl (2S)-2-[[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3/4-dihydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate (Remdesivir) having increased water solubility is disclosed, along with methods

Synthesis method of

The method comprises the following steps: (2R, 3R, 4S, 5R) -2 - (4 - 2) [1 - f, 1, 2] triazine 4-yl) -7 -3-hydroxy 4 - (hydroxymethyl) tetrahydrofuran -5 -2 - carbonitrile. 2,2 - Dimethoxypropane and first acid catalyst were added first solvent, stirred,