19191-91-4

Basic information

• Product Name: L-A-PHOSPHATIDYLCHOLINE, DIOCTANOYL
• Synonyms: [O-(1-O,2-O-Dioctanoyl-L-glycero-3-phospho)choline]anion;1,2-Dioctanoyl-L-3-phosphatidylcholine;Dicapryloyl-L-α-lecithin;Dicapryloylphosphatidylcholine;Dioctanoyl-L-α-glycerophosphorylcholine;L-Dioctanoylphosphatidylcholine;1,2-Dioctanoyl PC;Dioctanoyl-L-α-phosphatidylcholine
• CAS NO: 19191-91-4
• Molecular Formula: C24H48NO8P
• Molecular Weight: 509.613581
• Mol File: 19191-91-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: L-A-PHOSPHATIDYLCHOLINE, DIOCTANOYL(CAS DataBase Reference)
• NIST Chemistry Reference: L-A-PHOSPHATIDYLCHOLINE, DIOCTANOYL(19191-91-4)
• EPA Substance Registry System: L-A-PHOSPHATIDYLCHOLINE, DIOCTANOYL(19191-91-4)

Safety Data

• Hazardous Substances Data: 19191-91-4(Hazardous Substances Data)

Usage

Uses

08:0 PC (1,2-dioctanoyl-sn-glycero-3-phosphocholine/C8PC) has been used as a substrate to study the analytical capabilities of several methods to determine water soluble phospholipids containing choline (wCh-PL) and also to study the behavior of the its analytical signal in a synthetic serum matrix (data-Trol). It may also be used as a bicellar model to study their phase behavior and to form a lipid film to study its effect on P-glycoprotein′s (P-gp′s) activity/to compare its effect with TWEEN?80 and Cremophor?EL.

General Description

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Biochem/physiol Actions

Phosphatidylcholine?(PC) can form a hydrophobic surface in the mucus by acting as a surfactant to inhibit the penetrance of bacteria.

Upstream product

• 60514-48-9 1,2-dioctanoyl-sn-glycerol 
• 55357-38-5 choline tosylate 
• 10025-87-3 trichlorophosphate 

Downstream Products

• 45287-18-1 1-octanoyl-sn-glycero-3-phosphocholine 

Relevant articles and documents

Stereochemical Analysis of Glycerophospholipids by Vibrational Circular Dichroism

The stereochemistry of glycerophospholipids (GPLs) has been of interest for its roles in the evolution of life and in their biological activity. However, because of their structural complexity, no convenient method to determine their configuration has been reported. In this work, through the first systematic application of vibrational circular dichroism (VCD) spectroscopy to various diacylated GPLs, we have revealed that their chirality can be assigned by the sign of a VCD exciton couplet generated by the interaction of two carbonyl groups. This paper also presents spectroscopic evidence for the stereochemistry of GPLs isolated from bacteria, eukaryotes, and mitochondria.