1921-90-0

Basic information

• Product Name: (E)-2-benzylidenecyclopentanone
• Synonyms: (E)-2-benzylidenecyclopentanone
• CAS NO: 1921-90-0
• Molecular Formula: C₁₂H₁₂O
• Molecular Weight: 172.22308
• Mol File: 1921-90-0.mol
• Article Data: 54

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (E)-2-benzylidenecyclopentanone(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-benzylidenecyclopentanone(1921-90-0)
• EPA Substance Registry System: (E)-2-benzylidenecyclopentanone(1921-90-0)

Safety Data

• Hazardous Substances Data: 1921-90-0(Hazardous Substances Data)

Usage

General Description

(E)-2-benzylidenecyclopentanone is a chemical compound with the molecular formula C11H12O. It is a yellow crystalline solid that is commonly used in the synthesis of various organic compounds. (E)-2-benzylidenecyclopentanone is known for its versatile reactivity and is often utilized in the production of pharmaceuticals, fragrances, and other fine chemicals. Its unique structure and properties make it a valuable building block in organic synthesis, and it is widely used in research and industrial applications. Additionally, (E)-2-benzylidenecyclopentanone has been shown to exhibit biological activity and may have potential therapeutic benefits in medicine. Overall, this chemical compound plays a significant role in the fields of chemistry and pharmaceutical science due to its diverse applications and potential benefits.

Upstream product

• 100-52-7 benzaldehyde 
• 120-92-3 cyclopentanone 
• 936-52-7 1-(N-morpholino)cyclopent-1-ene 
• 19980-43-9 1-(trimethylsilyloxy)cyclopentene 
• 545376-56-5 1-trichloroacetoxycyclopentene 
• 130602-09-4 6-phenylhex-5-yn-1-al 
• 913708-40-4 1-(trichloromethyl)cyclobutanol 
• 57204-92-9 2-Benzyl-2-phenylselenocyclopentanon 
• 201230-82-2 carbon monoxide 
• 57718-13-5 (5-bromo-pent-1-ynyl)-benzene 
• 95127-15-4 methyl 3-(hydroxy(phenyl)methyl)-2-oxocyclopentanecarboxylate 
• 5581-75-9 6-phenylhexanic acid 
• 1056246-36-6 2-bromocyclopentanone 
• 94708-08-4 4-(5-benzyliden-1-cyclopenten-1-yl)morpholine 

Downstream Products

• 2867-63-2 2-benzylcyclopentanone 
• 58738-53-7 (E)-2-(phenylmethylene)cyclopentanol 
• 13694-31-0 (1SR,2RS)-α-benzylcyclopentanol 
• 895-80-7 2,5-dibenzylidenecyclopentanone 
• 109451-22-1 2-ethoxy-4-phenyl-2,3,4,5,6,7-hexahydro-cyclopenta[b]pyran 
• 110-94-1 1,5-pentanedioic acid 
• 100-52-7 benzaldehyde 
• 130954-49-3 [2-Methylene-cyclopent-(E)-ylidenemethyl]-benzene 
• 66660-63-7 2-[1-Phenyl-meth-(E)-ylidene]-cyclopentanone oxime 
• 140846-05-5 11-Phenyl-2,3,4,11-tetrahydro-1H-benzo[4,5]imidazo[1,2-a]cyclopenta[d]pyrimidine 
• 77821-81-9 7-Benzylidene-3-cyano-2-oxo-4-phenyl-2,5,6,7-tetrahydro-1H-1-pyrindine 
• 55525-94-5 5-amino-7-phenylindane-4,6-dicarbonitrile 
• 107626-24-4 (+/-)(1Ξ)-trans-2-[(Ξ)-α-(4-methyl-piperazino)-benzyl]-cyclopentanol 
• 107626-24-4 (+/-)(1Ξ)-cis-2-[(Ξ)-α-(4-methyl-piperazino)-benzyl]-cyclopentanol 

Relevant articles and documents

Synthesis of unsymmetrical dienones with heteroaromatic substituents

Condensation of heteroaromatic aldehydes with 2-benzylidenecyclopentanone in a basic medium afforded a number of unsymmetrical 2,5- diarylidenecyclopentanones. According to 1H NMR data, the dienones obtained were the E,E-isomers.

Design and Green Synthesis of Piperlongumine Analogs and Their Antioxidant Activity against Cerebral Ischemia-Reperfusion Injury

The supplementation of exogenous antioxidants to scavenge excessive reactive oxygen species (ROS) is an effective treatment for cerebral ischemia-reperfusion injury (CIRI) in stroke. Piperlongumine (PL), a natural alkaloid, has a great potential as a neur

Highly Enantioselective Iridium-Catalyzed Hydrogenation of Conjugated Trisubstituted Enones

Asymmetric hydrogenation of conjugated enones is one of the most efficient and straightforward methods to prepare optically active ketones. In this study, chiral bidentate Ir-N,P complexes were utilized to access these scaffolds for ketones bearing the stereogenic center at both the α- and β-positions. Excellent enantiomeric excesses, of up to 99%, were obtained, accompanied with good to high isolated yields. Challenging dialkyl substituted substrates, which are difficult to hydrogenate with satisfactory chiral induction, were hydrogenated in a highly enantioselective fashion.

Donor-acceptor bicyclopropyl configuration-fixed by an additional trimethylene bridge: synthesis and Lewis acid-catalyzed tandem three-membered rings opening

A diastereoselective synthesis of donor-acceptor bicyclopropyl, 8-phenyldispiro[2.3.2.0]-nonane-1,1-dicarboxylate, was carried out, which treated with Lewis acids acts as a synthetic equivalent of cis-1,6-zwitterionic intermediates. In the presence of GaC