1928-38-7

Basic information

• Product Name: Methyl (2,4-dichlorophenoxy)acetate
• Synonyms: Aceticacid, (2,4-dichlorophenoxy)-, methyl ester (6CI,7CI,8CI,9CI);(2,4-Dichlorophenoxy)acetic acid methyl ester; 2,4-D methyl ester; Methyl(2,4-dichlorophenoxy)acetate; NSC 9399
• CAS NO: 1928-38-7
• Molecular Formula: C₉H₈Cl₂O₃
• Molecular Weight: 235.07
• EINECS: 217-670-7
• Mol File: 1928-38-7.mol
• Article Data: 36

Chemical Properties

• Boiling Point: 298.3°Cat760mmHg
• Flash Point: 124.1°C
• Appearance: /
• Density: 1.352g/cm³
• Vapor Pressure: 0.000385mmHg at 25°C
• Refractive Index: 1.53
• CAS DataBase Reference: Methyl (2,4-dichlorophenoxy)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl (2,4-dichlorophenoxy)acetate(1928-38-7)
• EPA Substance Registry System: Methyl (2,4-dichlorophenoxy)acetate(1928-38-7)

Safety Data

• Hazardous Substances Data: 1928-38-7(Hazardous Substances Data)

Usage

General Description

Methyl (2,4-dichlorophenoxy)acetate, also known as 2,4-DMA, is a synthetic organic compound that is derived from the herbicide 2,4-D. It is commonly used as a pesticide and herbicide to control a wide range of broadleaf weeds in various crops. 2,4-DMA works by mimicking the growth hormone in plants, causing uncontrolled growth and eventually leading to the death of the targeted weeds. However, the use of 2,4-DMA has been a subject of controversy due to potential health and environmental concerns. Studies have linked it to increased risks of cancer, reproductive problems, and ecological harm. As a result, its use is heavily regulated in many countries to minimize its potential negative impacts.

InChI:InChI=1/C9H8Cl2O3/c1-6(12)13-5-14-9-3-2-7(10)4-8(9)11/h2-4H,5H2,1H3

Upstream product

• 67-56-1 methanol 
• 94-75-7 2,4-Dichlorophenoxyacetic acid 
• 6212-47-1 n-propyl phenoxyacetate 
• 2065-23-8 methyl 2-phenoxyacetate 
• 108-95-2 phenol 
• 96-32-2 bromoacetic acid methyl ester 
• 120-83-2 2,4-dichlorophenol 
• 112-62-9 Methyl oleate 
• 96-34-4 methyl chloroacetate 
• 2008-39-1 2,4-dichlorophenoxyacetic acid dimethylamine 
• 74-88-4 methyl iodide 

Downstream Products

• 14900-87-9 hexadecyl 2-(2,4-dichlorophenoxy)acetate 
• 120-83-2 2,4-dichlorophenol 
• 774-74-3 2-(2,4-dichlorophenoxy)acetyl chloride 
• 94-75-7 2,4-Dichlorophenoxyacetic acid 
• 74-87-3 methylene chloride 
• 1713-15-1 2,4-dichlorophenoxyacetic acid isobutyl ester 
• 62855-71-4 lauryl 2,4-dichlorophenoxyacetate 
• 65267-97-2 2,4-dichlorophenoxyacetic acid cyclohexyl ester 
• 533-23-3 ethyl 2,4-dichlorophenoxyacetate 
• 94-80-4 Fernesta 
• 3035-67-4 2,4-dichlorophenoxyacetic acid isooctyl ester 
• 2008-39-1 2,4-dichlorophenoxyacetic acid dimethylamine 

Relevant articles and documents

Glove permeation tests using novel microchemical techniques for 2,4- dichlorophenoxyacetic acid (2,4-D) derivatives

The aim was to assess the permeation of different herbicide emulsion concentrate formulations of 2,4-dichlorophenoxyacetic acid (2,4-D) as 60.8 and 83.5% butoxyethy] ester (BEE) and 46.8% dimethyl amine salt (DMAS) through four types of glove materials (l

Carboxylic Acid Reductase Can Catalyze Ester Synthesis in Aqueous Environments

Most of the well-known enzymes catalyzing esterification require the minimization of water or activated substrates for activity. This work reports a new reaction catalyzed by carboxylic acid reductase (CAR), an enzyme known to transform a broad spectrum of carboxylic acids into aldehydes, with the use of ATP, Mg2+, and NADPH as co-substrates. When NADPH was replaced by a nucleophilic alcohol, CAR from Mycobacterium marinum can catalyze esterification under aqueous conditions at room temperature. Addition of imidazole, especially at pH 10.0, significantly enhanced ester production. In comparison to other esterification enzymes such as acyltransferase and lipase, CAR gave higher esterification yields in direct esterification under aqueous conditions. The scalability of CAR catalyzed esterification was demonstrated for the synthesis of cinoxate, an active ingredient in sunscreen. The CAR esterification offers a new method for green esterification under high water content conditions.

ACLY INHIBITORS AND USES THEREOF

The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.