19300-54-0Relevant articles and documents
Synthesis of new amphiphilic perfluoroalkylated bipyridines
Garelli,Vierling
, p. 3046 - 3051 (1992)
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Fine-tuning latent fingerprint detection on paper using 1,2-indanedione bi-functional reagents
Lee, Jisun,Joullié, Madeleine M.
, p. 7620 - 7629 (2015)
In order to address the need for consistency and generality in chemical methods developed for detection of latent fingerprints on paper substrates, a practical protocol was developed using 1,2-indanedione-based bi-functional reagents. A series of novel bi
Metal-free Photochemical Atom Transfer Radical Addition (ATRA) of BrCCl3 to Alkenes
Nikitas, Nikolaos F.,Voutyritsa, Errika,Gkizis, Petros L.,Kokotos, Christoforos G.
supporting information, p. 96 - 101 (2021/01/04)
A simple, photochemical, and metal-free protocol for the atom transfer radical addition (ATRA) of bromotrichloromethane onto various alkenes is described. Among a range of organic molecules, phenylglyoxylic acid proved to be the most suitable photoinitiator to promote a sustainable process for the addition of bromotrichloromethane to olefins. This photochemical atom transfer radical protocol can be expanded into a wide substrate scope of aliphatic olefins bearing various functional groups, leading to the corresponding products in good to excellent yields.
Synthesis and characterization of light-fluorous NHC-ligands and their palladium complexes
Horváth, István T.,Lo, Angel S. W.,Yiu, Ken S. M.
, (2020/12/14)
Light-fluorous ponytails containing perfluoro-n-propyl, perfluoro-n-butyl and perfluoro-t-butoxy groups were used to synthesize light-fluorous α-olefins, branched dialkyl iodides, alkyl triflates, alkyl imidazoles, and dialkyl imidazolium salts. The latte
Fluorofunctionalization of C=C Bonds with Selectfluor: Synthesis of β-Fluoropiperazines through a Substrate-Guided Reactivity Switch
Capilato, Joseph N.,Bume, Desta Doro,Lee, Wei Hao,Hoffenberg, Louis E. S.,Jokhai, Rayyan Trebonias,Lectka, Thomas
, p. 14234 - 14244 (2019/01/03)
The halofunctionalization of alkene substrates remains an essential tool for synthetic chemists. Herein, we report regioselective ammoniofluorination of unactivated alkenes through photochemical means. A one-pot transformation of the ammonium fluoride products into pharmaceutically relevant β-fluoropiperazines is highlighted. Furthermore, a substrate-guided reactivity switch is observed: certain alkenes are shown to react with the same fluorinating reagent to instead give the less-substituted fluoride. We hope that the ammoniofluorination reaction will be of utility in the area of medicinal chemistry, where nitrogen and fluorine are among the most important heteroatoms.