1934-71-0

Basic information

• Product Name: 1-PHENYLCYCLOHEXYLAMINE HYDROCHLORIDE
• Synonyms: 1-PHENYLCYCLOHEXYLAMINE HYDROCHLORIDE;1-fenilcicloesilamminaclorhidrato;1-phenyl-cyclohexylaminhydrochloride;1-PHENYLCYCLOHEXYLAMINE HYDROCHLORIDE, 95+%;1-phenylcyclohexanamine hydrochloride;1-phenylcyclohexan-1-aMine hydrochloride;1-PhenylcyclohexylaMine HCl;Cyclohexanamine, 1-phenyl-, hydrochloride
• CAS NO: 1934-71-0
• Molecular Formula: C₁₂H₁₇N*ClH
• Molecular Weight: 211.73
• EINECS: 604-604-1
• Mol File: 1934-71-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 247-248 °C
• Boiling Point: 273.1°C at 760 mmHg
• Flash Point: 121.6 °C
• Appearance: /
• Density: 0.992 g/cm³
• Vapor Pressure: 0.00586mmHg at 25°C
• CAS DataBase Reference: 1-PHENYLCYCLOHEXYLAMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PHENYLCYCLOHEXYLAMINE HYDROCHLORIDE(1934-71-0)
• EPA Substance Registry System: 1-PHENYLCYCLOHEXYLAMINE HYDROCHLORIDE(1934-71-0)

Safety Data

• Hazardous Substances Data: 1934-71-0(Hazardous Substances Data)

Usage

General Description

1-Phenylcyclohexylamine Hydrochloride is a chemical compound known for its use as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is a hydrochloride salt form of the amine compound 1-Phenylcyclohexylamine, which is a derivative of cyclohexylamine. 1-Phenylcyclohexylamine Hydrochloride is a white to off-white crystalline powder that is soluble in water and ethanol. It is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and active pharmaceutical ingredients. It is also used as a research chemical and may have potential applications in other industries such as agrochemicals and materials science.

InChI:InChI=1/C12H17N.ClH/c13-12(9-5-2-6-10-12)11-7-3-1-4-8-11;/h1,3-4,7-8H,2,5-6,9-10,13H2;1H

Upstream product

• 1934-58-3 Benzyl-(1-phenyl-cyclohexyl)-amine; hydrochloride 
• 2890-60-0 1-phenylcyclohexane-1-carboxamide 
• 66021-71-4 1-(1-azidocyclohexyl)benzene 
• 1589-60-2 1-phenylcyclohexanol 
• 2201-24-3 1-phenylcyclohexylamine 
• 100-47-0 benzonitrile 
• 23708-48-7 pentamethylenebis(magnesium bromide) 

Downstream Products

• 93185-14-9 5-valeraldehyde ethylene acetal 
• 5769-29-9 N-<4-Chlor-benzolsulfonyl>-N'-<1-phenyl-cyclohexyl>-harnstoff 

Relevant articles and documents

Oxadiazole Amine Derivative Compounds as Histone Deacetylase 6 Inhibitor, and the Pharmaceutical Composition Comprising the same

The present invention relates to a novel compound having an activity of inhibiting histone deacetylase 6 (HDAC6), an optical isomer thereof or a pharmaceutically acceptable salt thereof, a use thereof for preparation of a drug for treatment, a pharmaceutical composition comprising the same, a treatment method using the composition, and a method for preparing the same. The novel compound, an optical isomer thereof or a pharmaceutically acceptable salt thereof according to the present invention has an activity of inhibiting histone deacetylase 6 (HDAC6), and is effective for preventing or treating HDAC6-related diseases, including infectious diseases; neoplasm; endocrine, nutritional and metabolic diseases; mental and behavior disorders; nerve disorders; eye and adnexa diseases; cardiovascular diseases; respiratory diseases; digestive organ diseases; skin and subcutaneous tissue diseases; musculoskeletal and connective tissue diseases; or congenital malformation, deformation and chromosomal abnormality.COPYRIGHT KIPO 2017

1-Substituted cyclopentylamines from nitriles and tetramethylenebismagnesium dibromide in the presence of Ti(OiPr)4

Various 1-substituted cyclopentylamines (25 examples, 1089 % yield) have been prepared according to a one-pot procedure by the addition of tetramethylenebismagnesium. di- bromide in the presence of Ti(OiPr)4 to aliphatic, aromatic and heteroaromatic nitriles, respectively.