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19468-31-6

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19468-31-6 Usage

General Description

17β-hydroxy-19-nor-5β-androstan-3-one, also known as mibolerone, is a synthetic anabolic steroid that is derived from nandrolone. It is a potent androgenic steroid that is used in veterinary medicine to promote muscle growth and improve the appetite and weight of livestock. Mibolerone is not approved for human use and is classified as a Schedule III controlled substance in the United States due to its potential for misuse and abuse. It is known for its strong androgenic effects and is often used by bodybuilders and athletes to enhance athletic performance. However, it is also associated with a range of adverse effects, including liver toxicity, cardiovascular complications, and reproductive issues. Therefore, its use in humans is strongly discouraged.

Check Digit Verification of cas no

The CAS Registry Mumber 19468-31-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,4,6 and 8 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 19468-31:
(7*1)+(6*9)+(5*4)+(4*6)+(3*8)+(2*3)+(1*1)=136
136 % 10 = 6
So 19468-31-6 is a valid CAS Registry Number.

19468-31-6Relevant articles and documents

Neurosteroid analogues. 4. The effect of methyl substitution at the C-5 and C-10 positions of neurosteroids on electrophysiological activity at GABA(A) receptors

Han, Mingcheng,Zorumski, Charles F.,Covey, Douglas F.

, p. 4218 - 4232 (1996)

A series of analogues of the neuroactive steroids 3α-hydroxy-5α- pregnan-20-one and 3α-hydroxy-5β-pregnan-20-one were studied to elucidate the mode of binding of 5α- and 5β-reduced steroids to steroid binding sites on GABA(A) receptors. Analogues which were either 3α-hydroxy-20-ketosteroids or 3α-hydroxysteroid-17β-carbonitriles and which contained various methyl group substitution patterns at C-5 and C-10 were prepared. Evaluations utilized whole-cell patch clamp electrophysiological methods carried out on cultured rat hippocampal neurons, and the results obtained with the rigid 17β-carbonitrile analogs were analyzed using molecular modeling methods. The molecular modeling results provide a rationale for the observation that the configuration of the hydroxyl group at C-3 is a greater determinant of anesthetic potency than the configuration of the A,B ring fusion at C-5. The electrophysiological results identify steric restrictions for the space that can be occupied in 5α- and 5β-reduced steriod modulators of GABA(A) recepters in the regions of space proximate to the steroid C-5, C-10, and possibly C-4 positions. This information is useful for the development of nonsteroidal analogues that can modulate GABA(A) receptors via interactions at steroid binding sites.

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