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FMOC-L-HOLys(BOC)-OH, also known as N-(9-fluorenylmethoxycarbonyl)-L-homolysine (tert-butoxycarbonyl)-OH, is a chemical compound that is a derivative of the amino acid lysine. It features the FMOC group as a protecting group for the amine functional group and the BOC group as a protecting group for the carboxyl functional group. FMOC-L-HOLYS(BOC)-OH is integral in the field of organic chemistry, particularly in peptide synthesis.

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  • Fmoc-L-HomoLys(Boc)-OH, (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-7-[(2-methylpropan-2-yl)oxycarbonylamino]heptanoic acid, MFCD01860606

    Cas No: 194718-17-7

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  • 194718-17-7 Structure
  • Basic information

    1. Product Name: FMOC-L-HOLYS(BOC)-OH
    2. Synonyms: FMOC-L-HLYS(BOC);FMOC-L-HOLYS(BOC)-OH;FMOC-D, L-HLYS(BOC);N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-ZETA-T-BUTYLOXYCARBONYL-L-HOMOLYSINE;N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-ZETA-TERT-BUTYLOXYCARBONYL-HOMO-L-LYSINE;N-ALPHA-(9-FLUOROENYLMETHYLOXYCARBONYL)-N-ZETA-T-BUTYLOXYCARBONYL-L-HOMOLYSINE;(S)-FMoc-2-aMino-7-(Boc-aMino)-heptanoic acid;(9H-Fluoren-9-yl)MethOxy]Carbonyl L-HomoLysine(Boc)-OH
    3. CAS NO:194718-17-7
    4. Molecular Formula: C27H34N2O6
    5. Molecular Weight: 482.57
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 194718-17-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 692.7±55.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.195±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 3.90±0.21(Predicted)
    10. CAS DataBase Reference: FMOC-L-HOLYS(BOC)-OH(CAS DataBase Reference)
    11. NIST Chemistry Reference: FMOC-L-HOLYS(BOC)-OH(194718-17-7)
    12. EPA Substance Registry System: FMOC-L-HOLYS(BOC)-OH(194718-17-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 194718-17-7(Hazardous Substances Data)

194718-17-7 Usage

Uses

Used in Organic Chemistry:
FMOC-L-HOLYS(BOC)-OH is used as a building block in peptide synthesis for the creation of longer peptide chains. Its role is crucial in solid-phase peptide synthesis, where the FMOC and BOC protecting groups are selectively removed to facilitate the addition of other amino acids, thus extending the peptide chain.
Used in Pharmaceutical Development:
In the pharmaceutical industry, FMOC-L-HOLYS(BOC)-OH is utilized as a reagent in the preparation of peptide-based drugs. Its protective groups ensure that the peptide synthesis process can be controlled and specific, which is essential for the development of targeted and effective therapeutics.
Used in Research:
FMOC-L-HOLYS(BOC)-OH also serves as a valuable research tool in the study of protein-protein interactions. By incorporating this compound into peptides, researchers can investigate and understand the mechanisms of these interactions, which is fundamental for advancing knowledge in biochemistry and molecular biology.

Check Digit Verification of cas no

The CAS Registry Mumber 194718-17-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,7,1 and 8 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 194718-17:
(8*1)+(7*9)+(6*4)+(5*7)+(4*1)+(3*8)+(2*1)+(1*7)=167
167 % 10 = 7
So 194718-17-7 is a valid CAS Registry Number.

194718-17-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name FMOC-L-HOLYS(BOC)-OH

1.2 Other means of identification

Product number -
Other names FMOC-D,L-HLYS(BOC)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:194718-17-7 SDS

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