196496-26-1

Basic information

• Product Name: 1-(2-methylphenyl)indole-3-carboxaldehyde
• Synonyms: 1-(2-methylphenyl)indole-3-carboxaldehyde;1-(2-Methylphenyl)-1H-indole-3-carbaldehyde
• CAS NO: 196496-26-1
• Molecular Formula: C₁₆H₁₃NO
• Molecular Weight: 235
• Mol File: 196496-26-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(2-methylphenyl)indole-3-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-methylphenyl)indole-3-carboxaldehyde(196496-26-1)
• EPA Substance Registry System: 1-(2-methylphenyl)indole-3-carboxaldehyde(196496-26-1)

Safety Data

• Hazardous Substances Data: 196496-26-1(Hazardous Substances Data)

Upstream product

• 487-89-8 Indole-3-carboxaldehyde 
• 615-37-2 ortho-methylphenyl iodide 

Relevant articles and documents

New 1-arylindoles based serotonin 5-HT7 antagonists. Synthesis and binding evaluation studies

Based on 5-HT1A and 5-HT7 ligand MR25003 scaffold, a new series of 1-aryl indole analogues were prepared and evaluated against 5-HT7 receptors. Modulations of aryl moieties provided a large number of new indolic derivative

Unexpected C2-arylation of 1-(pyridin-2-yl)indole-3-carboxaldehyde mediated by copper

The C2-arylation of 1-(pyridin-2-yl)indole-3-carboxaldehyde with aryl iodides was carried out in the presence of Cu2O in basic medium. This simple and efficient method led to the preparation of 1,2-diarylindole derivatives. Georg Thieme Verlag Stuttgart.